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Gene: COPS8 (COP9 signalosome subunit 8) Homo sapiens
Symbol: COPS8
Name: COP9 signalosome subunit 8
Description: Involved in activation of NF-kappaB-inducing kinase activity; cellular protein modification process; and negative regulation of cell population proliferation. Localizes to the cytosol; nucleus; and perinuclear region of cytoplasm.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: COP9; COP9 constitutive photomorphogenic homolog subunit 8; COP9 homolog; COP9 signalosome complex subunit 8; CSN8; hCOP9; JAB1-containing signalosome subunit 8; MGC1297; MGC43256; SGN8; signalosome subunit 8
Mus musculus (house mouse) : Cops8 (COP9 signalosome subunit 8)  MGI  Alliance
Rattus norvegicus (Norway rat) : Cops8 (COP9 signalosome subunit 8)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Cops8 (COP9 signalosome subunit 8)
Pan paniscus (bonobo/pygmy chimpanzee) : COPS8 (COP9 signalosome subunit 8)
Canis lupus familiaris (dog) : COPS8 (COP9 signalosome subunit 8)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Cops8 (COP9 signalosome subunit 8)
Sus scrofa (pig) : COPS8 (COP9 signalosome subunit 8)
Chlorocebus sabaeus (African green monkey) : COPS8 (COP9 signalosome subunit 8)
Heterocephalus glaber (naked mole-rat) : Cops8 (COP9 signalosome subunit 8)
more info ...
Related Pseudogenes: COPS8P1   COPS8P2   COPS8P3  
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38 Ensembl2237,085,882 - 237,100,474 (+)EnsemblGRCh38hg38GRCh38
GRCh382237,085,441 - 237,100,474 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh372237,993,870 - 238,007,489 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362237,658,823 - 237,672,228 (+)NCBINCBI36hg18NCBI36
Celera2231,707,494 - 231,720,899 (+)NCBI
Cytogenetic Map2q37.3NCBI
HuRef2229,786,783 - 229,800,188 (+)NCBIHuRef
CHM1_12238,000,165 - 238,013,570 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on COPS8
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1322849
Created: 2005-01-12
Species: Homo sapiens
Last Modified: 2020-03-24
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.