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Gene: ARHGEF18 (Rho/Rac guanine nucleotide exchange factor 18) Homo sapiens
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Symbol: ARHGEF18
Name: Rho/Rac guanine nucleotide exchange factor 18
Description: Exhibits guanyl-nucleotide exchange factor activity. Involved in several processes, including negative regulation of stress fiber assembly; protein localization to cell-cell junction; and small GTPase mediated signal transduction. Localizes to the apical part of cell; cytosol; and plasma membrane. Implicated in retinitis pigmentosa.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: 114 kDa Rho-specific guanine nucleotide exchange factor; KIAA0521; MGC15913; P114-RHO-GEF; P114-RhoGEF; p114RhoGEF; rho guanine nucleotide exchange factor 18; Rho-specific guanine nucleotide exchange factor p114; Rho/Rac guanine nucleotide exchange factor (GEF) 18; RP78; SA-RhoGEF; septin-associated RhoGEF
Orthologs:
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38197,348,901 - 7,476,990 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37197,420,481 - 7,537,371 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36197,351,866 - 7,443,371 (+)NCBINCBI36hg18NCBI36
Build 34197,351,865 - 7,443,370NCBI
Celera197,331,115 - 7,409,876 (+)NCBI
Cytogenetic Map19p13.2NCBI
HuRef197,186,895 - 7,208,106 (+)NCBIHuRef
HuRef197,128,031 - 7,179,714 (+)NCBIHuRef
CHM1_1197,459,437 - 7,537,381 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
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References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on ARHGEF18
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1322915
Created: 2005-01-12
Species: Homo sapiens
Last Modified: 2019-10-16
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.