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Gene: CDKN1C (cyclin dependent kinase inhibitor 1C) Homo sapiens
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Symbol: CDKN1C
Name: cyclin dependent kinase inhibitor 1C
Description: Exhibits protein kinase inhibitor activity. Involved in several processes, including negative regulation of cyclin-dependent protein kinase activity; positive regulation of transforming growth factor beta receptor signaling pathway; and regulation of transcription, DNA-templated. Localizes to the cytoplasm and nucleus. Implicated in Beckwith-Wiedemann syndrome; IMAGe syndrome; and hyperinsulinism.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: BWCR; BWS; cyclin-dependent kinase inhibitor 1C; cyclin-dependent kinase inhibitor 1C (p57, Kip2); cyclin-dependent kinase inhibitor p57; IMAGE; KIP2; p57; p57Kip2; WBS
Orthologs:
Mus musculus (house mouse) : Cdkn1c (cyclin-dependent kinase inhibitor 1C (P57))  MGI  Alliance
Rattus norvegicus (Norway rat) : Cdkn1c (cyclin-dependent kinase inhibitor 1C)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Cdkn1c (cyclin dependent kinase inhibitor 1C)
Sus scrofa (pig) : CDKN1C (cyclin dependent kinase inhibitor 1C)
Chlorocebus sabaeus (African green monkey) : CDKN1C (cyclin dependent kinase inhibitor 1C)
Heterocephalus glaber (naked mole-rat) : Cdkn1c (cyclin dependent kinase inhibitor 1C)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38 Ensembl112,883,213 - 2,885,773 (-)EnsemblGRCh38hg38GRCh38
GRCh38112,883,218 - 2,885,775 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37112,904,448 - 2,907,063 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36112,861,441 - 2,863,551 (-)NCBINCBI36hg18NCBI36
Build 34112,861,440 - 2,863,537NCBI
Celera112,939,161 - 2,941,708 (-)NCBI
Cytogenetic Map11p15.4NCBI
HuRef112,692,706 - 2,695,485 (-)NCBIHuRef
CHM1_1112,903,367 - 2,905,909 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
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Molecular Pathway Annotations
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References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on CDKN1C
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1322980
Created: 2005-01-12
Species: Homo sapiens
Last Modified: 2020-03-24
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.