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Gene: AMFR (autocrine motility factor receptor) Homo sapiens
Symbol: AMFR
Name: autocrine motility factor receptor
Description: Exhibits several functions, including BAT3 complex binding activity; chaperone binding activity; and ubiquitin-specific protease binding activity. Involved in several processes, including endoplasmic reticulum unfolded protein response; protein ubiquitination; and ubiquitin-dependent ERAD pathway. Localizes to several cellular components, including the Golgi apparatus; endoplasmic reticulum membrane; and perinuclear region of cytoplasm.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: AMF receptor, isoform 1; AMF receptor, isoform 2; autocrine motility factor receptor, E3 ubiquitin protein ligase; autocrine motility factor receptor, isoform 1; autocrine motility factor receptor, isoform 2; E3 ubiquitin-protein ligase AMFR; GP78; RING finger protein 45; RING-type E3 ubiquitin transferase AMFR; RNF45
Mus musculus (house mouse) : Amfr (autocrine motility factor receptor)  MGI  Alliance
Rattus norvegicus (Norway rat) : Amfr (autocrine motility factor receptor)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Amfr (autocrine motility factor receptor)
Pan paniscus (bonobo/pygmy chimpanzee) : AMFR (autocrine motility factor receptor)
Canis lupus familiaris (dog) : AMFR (autocrine motility factor receptor)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Amfr (autocrine motility factor receptor)
Sus scrofa (pig) : AMFR (autocrine motility factor receptor)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh381656,361,452 - 56,425,545 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh371656,395,364 - 56,459,450 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361654,952,865 - 55,016,945 (-)NCBINCBI36hg18NCBI36
Build 341654,952,864 - 55,016,804NCBI
Celera1640,892,193 - 40,957,463 (-)NCBI
Cytogenetic Map16q13NCBI
HuRef1642,266,003 - 42,329,606 (-)NCBIHuRef
CHM1_11657,802,735 - 57,866,433 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status



Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on AMFR
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1323068
Created: 2005-01-12
Species: Homo sapiens
Last Modified: 2019-11-26
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.