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Gene: E2F4 (E2F transcription factor 4) Homo sapiens
Symbol: E2F4
Name: E2F transcription factor 4
Description: Exhibits several functions, including DNA-binding transcription factor activity; RNA polymerase II proximal promoter sequence-specific DNA binding activity; and promoter-specific chromatin binding activity. Involved in positive regulation of transcription by RNA polymerase II. Localizes to the nuclear chromatin and nucleoplasm.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: E2F transcription factor 4, p107/p130-binding; E2F-4; p107/p130-binding protein; transcription factor E2F4
Mus musculus (house mouse) : E2f4 (E2F transcription factor 4)  MGI  Alliance
Rattus norvegicus (Norway rat) : E2f4 (E2F transcription factor 4)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : E2f4 (E2F transcription factor 4)
Pan paniscus (bonobo/pygmy chimpanzee) : E2F4 (E2F transcription factor 4)
Canis lupus familiaris (dog) : E2F4 (E2F transcription factor 4)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : E2f4 (E2F transcription factor 4)
Sus scrofa (pig) : E2F4 (E2F transcription factor 4)
more info ...
Related Pseudogenes: E2F4P1  
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh381667,192,155 - 67,198,918 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371667,226,068 - 67,232,821 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361665,783,569 - 65,790,322 (+)NCBINCBI36hg18NCBI36
Build 341665,783,568 - 65,790,322NCBI
Celera1651,734,300 - 51,741,053 (+)NCBI
Cytogenetic Map16q22.1NCBI
HuRef1653,099,244 - 53,105,997 (+)NCBIHuRef
CHM1_11668,633,395 - 68,640,148 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status



Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on E2F4
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1323111
Created: 2005-01-12
Species: Homo sapiens
Last Modified: 2019-11-26
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.