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Gene: Stap1 (signal transducing adaptor family member 1) Mus musculus
Symbol: Stap1
Name: signal transducing adaptor family member 1
Description: Exhibits SH3/SH2 adaptor activity; macrophage colony-stimulating factor receptor binding activity; and transmembrane receptor protein tyrosine kinase adaptor activity. Involved in several processes, including negative regulation of macrophage colony-stimulating factor signaling pathway; negative regulation of macrophage migration; and positive regulation of cellular component organization. Predicted to localize to the mitochondrion; nucleoplasm; and protein-containing complex. Orthologous to human STAP1 (signal transducing adaptor family member 1); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 3,4-methylenedioxymethamphetamine; buta-1,3-diene.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: AI586015; BCR downstream signaling 1; Brdg1; signal-transducing adaptor protein 1; STAP-1; stem cell adaptor protein 1; stem cell adaptor protein STAP-1
Homo sapiens (human) : STAP1 (signal transducing adaptor family member 1)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Stap1 (signal transducing adaptor family member 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Stap1 (signal transducing adaptor family member 1)
Pan paniscus (bonobo/pygmy chimpanzee) : STAP1 (signal transducing adaptor family member 1)
Canis lupus familiaris (dog) : STAP1 (signal transducing adaptor family member 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Stap1 (signal transducing adaptor family member 1)
Sus scrofa (pig) : STAP1 (signal transducing adaptor family member 1)
Chlorocebus sabaeus (African green monkey) : STAP1 (signal transducing adaptor family member 1)
Heterocephalus glaber (naked mole-rat) : Stap1 (signal transducing adaptor family member 1)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38 Ensembl586,071,746 - 86,106,125 (+)Ensembl
GRCm38586,071,584 - 86,106,125 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37586,500,853 - 86,533,018 (+)NCBIGRCm37mm9NCBIm37
MGSCv36587,146,389 - 87,178,554 (+)NCBImm8
Celera583,303,792 - 83,335,974 (+)NCBICelera
Cytogenetic Map5 E1NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Stap1
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1323119
Created: 2005-01-12
Species: Mus musculus
Last Modified: 2019-11-27
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.