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Gene: UBE2K (ubiquitin conjugating enzyme E2 K) Homo sapiens
Symbol: UBE2K
Name: ubiquitin conjugating enzyme E2 K
CRRD ID: 1323181
Description: Exhibits ubiquitin protein ligase binding activity and ubiquitin-ubiquitin ligase activity. Involved in several processes, including cellular response to interferon-beta; free ubiquitin chain polymerization; and positive regulation of cytokine-mediated signaling pathway. Predicted to localize to cytoplasm and nucleus.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: DKFZp564C1216; DKFZp686J24237; E2 ubiquitin-conjugating enzyme K; E2(25K); E2-25K; HIP-2; HIP2; huntingtin interacting protein 2; huntingtin-interacting protein 2; HYPG; LIG; UBC1; ubiquitin carrier protein; ubiquitin conjugating enzyme E2K; ubiquitin-conjugating enzyme E2 K; ubiquitin-conjugating enzyme E2(25K); ubiquitin-conjugating enzyme E2-25 KDA; ubiquitin-conjugating enzyme E2-25K; ubiquitin-conjugating enzyme E2K (UBC1 homolog, yeast); ubiquitin-protein ligase
Mus musculus (house mouse) : Ube2k (ubiquitin-conjugating enzyme E2K)  MGI  Alliance
Rattus norvegicus (Norway rat) : Ube2k (ubiquitin-conjugating enzyme E2K)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Ube2k (ubiquitin conjugating enzyme E2 K)
Pan paniscus (bonobo/pygmy chimpanzee) : UBE2K (ubiquitin conjugating enzyme E2 K)
Canis lupus familiaris (dog) : UBE2K (ubiquitin conjugating enzyme E2 K)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Ube2k (ubiquitin conjugating enzyme E2 K)
Sus scrofa (pig) : UBE2K (ubiquitin conjugating enzyme E2 K)
Chlorocebus sabaeus (African green monkey) : UBE2K (ubiquitin conjugating enzyme E2 K)
Heterocephalus glaber (naked mole-rat) : Ube2k (ubiquitin conjugating enzyme E2 K)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38.p13 Ensembl439,698,109 - 39,782,792 (+)EnsemblGRCh38hg38GRCh38
GRCh38439,698,136 - 39,782,792 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37439,699,664 - 39,784,412 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36439,376,266 - 39,457,977 (+)NCBINCBI36hg18NCBI36
Build 34439,522,436 - 39,604,148NCBI
Celera440,137,995 - 40,223,124 (+)NCBI
Cytogenetic Map4p14NCBI
HuRef439,024,547 - 39,109,580 (+)NCBIHuRef
CHM1_1439,699,339 - 39,784,070 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on UBE2K
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1323181
Created: 2005-01-12
Species: Homo sapiens
Last Modified: 2020-10-20
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.