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Gene: DAPK1 (death associated protein kinase 1) Homo sapiens
Symbol: DAPK1
Name: death associated protein kinase 1
Description: Exhibits several functions, including ATP binding activity; calmodulin binding activity; and syntaxin-1 binding activity. Involved in several processes, including cellular response to hydroperoxide; cellular response to interferon-gamma; and regulation of cellular protein metabolic process. Localizes to the actin cytoskeleton; cytoplasm; and plasma membrane. Implicated in urinary bladder cancer.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: DAP kinase 1; DAPK; death-associated protein kinase 1; DKFZp781I035; ROCO3
Mus musculus (house mouse) : Dapk1 (death associated protein kinase 1)  MGI  Alliance
Rattus norvegicus (Norway rat) : Dapk1 (death associated protein kinase 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Dapk1 (death associated protein kinase 1)
Pan paniscus (bonobo/pygmy chimpanzee) : DAPK1 (death associated protein kinase 1)
Canis lupus familiaris (dog) : DAPK1 (death associated protein kinase 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Dapk1 (death associated protein kinase 1)
Sus scrofa (pig) : DAPK1 (death associated protein kinase 1)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38987,497,228 - 87,708,634 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37990,112,601 - 90,323,566 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36989,302,576 - 89,513,369 (+)NCBINCBI36hg18NCBI36
Build 34987,342,349 - 87,553,097NCBI
Celera960,684,038 - 60,893,765 (+)NCBI
Cytogenetic Map9q21.33ENTREZGENE
HuRef959,938,084 - 60,147,991 (+)NCBIHuRef
CHM1_1990,259,940 - 90,471,316 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status



Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on DAPK1
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1323186
Created: 2005-01-12
Species: Homo sapiens
Last Modified: 2019-11-26
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.