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Gene: Stat2 (signal transducer and activator of transcription 2) Mus musculus
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Symbol: Stat2
Name: signal transducer and activator of transcription 2
Description: Predicted to have several functions, including DNA-binding transcription activator activity, RNA polymerase II-specific; identical protein binding activity; and ubiquitin-like protein ligase binding activity. Involved in type I interferon signaling pathway. Localizes to the cytoplasm and nucleus. Human ortholog(s) of this gene implicated in primary immunodeficiency disease. Is expressed in several structures, including central nervous system; early conceptus; and genitourinary system. Orthologous to human STAT2 (signal transducer and activator of transcription 2); PARTICIPATES IN interleukin-27 signaling pathway; hepatitis C pathway; influenza A pathway; INTERACTS WITH 17alpha-ethynylestradiol; 17beta-estradiol; 2,2',4,4'-Tetrabromodiphenyl ether.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 1600010G07Rik; AW496480
Orthologs:
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38 Ensembl10128,270,559 - 128,292,849 (+)EnsemblGRCm38mm10GRCm38
GRCm3810128,270,498 - 128,292,853 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv3710127,707,632 - 127,729,905 (+)NCBIGRCm37mm9NCBIm37
MGSCv3610127,673,525 - 127,695,798 (+)NCBImm8
Celera10130,656,386 - 130,681,169 (+)NCBICelera
Cytogenetic Map10 D3NCBI
cM Map1076.5NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Stat2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1323218
Created: 2005-01-12
Species: Mus musculus
Last Modified: 2020-01-21
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.