Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: PDCD1 (programmed cell death 1) Homo sapiens
Analyze
Symbol: PDCD1
Name: programmed cell death 1
Description: Involved in positive regulation of T cell apoptotic process. Predicted to localize to the plasma membrane. Implicated in lupus nephritis; multiple sclerosis; and systemic lupus erythematosus. Biomarker of renal cell carcinoma.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: CD279; hPD-1; hPD-l; hSLE1; PD-1; PD1; programmed cell death protein 1; SLEB2; systemic lupus erythematosus susceptibility 2
Orthologs:
Mus musculus (house mouse) : Pdcd1 (programmed cell death 1)  MGI  Alliance
Rattus norvegicus (Norway rat) : Pdcd1 (programmed cell death 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Pdcd1 (programmed cell death 1)
Canis lupus familiaris (dog) : PDCD1 (programmed cell death 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Pdcd1 (programmed cell death 1)
Sus scrofa (pig) : PDCD1 (programmed cell death 1)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382241,849,881 - 241,858,908 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh372242,792,033 - 242,801,058 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362242,440,711 - 242,449,731 (-)NCBINCBI36hg18NCBI36
Celera2236,456,683 - 236,465,707 (-)NCBI
Cytogenetic Map2q37.3NCBI
HuRef2234,541,510 - 234,550,535 (-)NCBIHuRef
CHM1_12242,797,131 - 242,806,156 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on PDCD1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1323231
Created: 2005-01-12
Species: Homo sapiens
Last Modified: 2019-11-05
Status: ACTIVE



NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.