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Gene: GET4 (guided entry of tail-anchored proteins factor 4) Homo sapiens
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Symbol: GET4
Name: guided entry of tail-anchored proteins factor 4
Description: Exhibits chaperone binding activity. Involved in cytoplasmic sequestering of protein; maintenance of unfolded protein involved in ERAD pathway; and tail-anchored membrane protein insertion into ER membrane. Localizes to the BAT3 complex; nucleolus; and nucleoplasm; INTERACTS WITH 2-hydroxypropanoic acid; arsane; arsenic atom.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: C7orf20; CEE; CGI-20; conserved edge expressed protein; conserved edge protein; conserved edge-expressed protein; golgi to ER traffic protein 4; Golgi to ER traffic protein 4 homolog; H_NH1244M04.5; transmembrane domain recognition complex 35 kDa subunit; transmembrane domain recognition complex, 35kDa; TRC35
Orthologs:
Mus musculus (house mouse) : Get4 (golgi to ER traffic protein 4)  MGI  Alliance
Rattus norvegicus (Norway rat) : Get4 (guided entry of tail-anchored proteins factor 4)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Get4 (guided entry of tail-anchored proteins factor 4)
Pan paniscus (bonobo/pygmy chimpanzee) : GET4 (guided entry of tail-anchored proteins factor 4)
Canis lupus familiaris (dog) : GET4 (guided entry of tail-anchored proteins factor 4)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Get4 (guided entry of tail-anchored proteins factor 4)
Sus scrofa (pig) : GET4 (guided entry of tail-anchored proteins factor 4)
Chlorocebus sabaeus (green monkey) : GET4 (guided entry of tail-anchored proteins factor 4)
Heterocephalus glaber (naked mole-rat) : Get4 (guided entry of tail-anchored proteins factor 4)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38 Ensembl7876,554 - 896,436 (+)Ensembl
GRCh387876,554 - 896,436 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh377916,191 - 936,073 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 367882,717 - 902,597 (+)NCBINCBI36hg18NCBI36
Build 347689,431 - 709,312NCBI
Celera7885,435 - 904,670 (+)NCBI
Cytogenetic Map7p22.3NCBI
HuRef7834,798 - 854,061 (+)NCBIHuRef
CHM1_17915,787 - 935,179 (+)NCBICHM1_1
CRA_TCAGchr7v27971,141 - 990,596 (+)NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on GET4
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1323234
Created: 2005-01-12
Species: Homo sapiens
Last Modified: 2020-01-07
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.