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Gene: Ttbk2 (tau tubulin kinase 2) Mus musculus
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Symbol: Ttbk2
Name: tau tubulin kinase 2
Description: Exhibits protein serine/threonine kinase activity. Involved in several processes, including embryonic brain development; nervous system development; and positive regulation of non-motile cilium assembly. Localizes to the centriole; ciliary basal body; and ciliary transition zone. Human ortholog(s) of this gene implicated in spinocerebellar ataxia type 11. Is expressed in nervous system. Orthologous to human TTBK2 (tau tubulin kinase 2); INTERACTS WITH 3,4-methylenedioxymethamphetamine; paracetamol; potassium dichromate.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 2610507N02Rik; AI326283; B930008N24Rik; KIAA0847; mKIAA0847; protein bartleby; tau-tubulin kinase 2; Ttbk; Ttbk1; TTK
Orthologs:
Homo sapiens (human) : TTBK2 (tau tubulin kinase 2)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Ttbk2 (tau tubulin kinase 2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Ttbk2 (tau tubulin kinase 2)
Pan paniscus (bonobo/pygmy chimpanzee) : TTBK2 (tau tubulin kinase 2)
Canis lupus familiaris (dog) : TTBK2 (tau tubulin kinase 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Ttbk2 (tau tubulin kinase 2)
Sus scrofa (pig) : TTBK2 (tau tubulin kinase 2)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
NCBI Annotation Information: Note: This record was renamed from Ttbk1 to Ttbk2 to conform to the annotation of human. [11 Apr 2007]
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm382120,732,816 - 120,850,584 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv372120,558,552 - 120,676,320 (-)NCBIGRCm37mm9NCBIm37
MGSCv362120,430,707 - 120,542,045 (-)NCBImm8
Celera2121,886,115 - 121,989,494 (-)NCBICelera
Cytogenetic Map2 E5NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Ttbk2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1323236
Created: 2005-01-12
Species: Mus musculus
Last Modified: 2019-10-16
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.