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Gene: Ttbk2 (tau tubulin kinase 2) Mus musculus
Symbol: Ttbk2
Name: tau tubulin kinase 2
Description: Exhibits protein serine/threonine kinase activity. Involved in several processes, including embryonic brain development; nervous system development; and positive regulation of non-motile cilium assembly. Localizes to the centriole; ciliary basal body; and ciliary transition zone. Human ortholog(s) of this gene implicated in spinocerebellar ataxia type 11. Is expressed in nervous system. Orthologous to human TTBK2 (tau tubulin kinase 2); INTERACTS WITH 3,4-methylenedioxymethamphetamine; paracetamol; potassium dichromate.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 2610507N02Rik; AI326283; B930008N24Rik; KIAA0847; mKIAA0847; protein bartleby; tau-tubulin kinase 2; Ttbk; Ttbk1; TTK
Homo sapiens (human) : TTBK2 (tau tubulin kinase 2)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Ttbk2 (tau tubulin kinase 2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Ttbk2 (tau tubulin kinase 2)
Pan paniscus (bonobo/pygmy chimpanzee) : TTBK2 (tau tubulin kinase 2)
Canis lupus familiaris (dog) : TTBK2 (tau tubulin kinase 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Ttbk2 (tau tubulin kinase 2)
Sus scrofa (pig) : TTBK2 (tau tubulin kinase 2)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
NCBI Annotation Information: Note: This record was renamed from Ttbk1 to Ttbk2 to conform to the annotation of human. [11 Apr 2007]
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm382120,732,816 - 120,850,584 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv372120,558,552 - 120,676,320 (-)NCBIGRCm37mm9NCBIm37
MGSCv362120,430,707 - 120,542,045 (-)NCBImm8
Celera2121,886,115 - 121,989,494 (-)NCBICelera
Cytogenetic Map2 E5NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Ttbk2
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1323236
Created: 2005-01-12
Species: Mus musculus
Last Modified: 2019-10-16
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.