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Gene: BUB1 (BUB1 mitotic checkpoint serine/threonine kinase) Homo sapiens
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Symbol: BUB1
Name: BUB1 mitotic checkpoint serine/threonine kinase
Description: Predicted to have protein kinase activity. Involved in regulation of sister chromatid cohesion. Localizes to the condensed nuclear chromosome outer kinetochore; cytosol; and nucleoplasm. Implicated in colorectal cancer.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: BUB1 budding uninhibited by benzimidazoles 1 homolog; BUB1, mitotic checkpoint serine/threonine kinase; BUB1A; BUB1L; budding uninhibited by benzimidazoles 1 homolog; hBUB1; mitotic checkpoint serine/threonine-protein kinase BUB1; mitotic spindle checkpoint kinase; putative serine/threonine-protein kinase
Orthologs:
Related Pseudogenes: BUB1P1  
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38 Ensembl2110,637,528 - 110,678,063 (-)Ensembl
GRCh382110,637,528 - 110,678,107 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh372111,395,275 - 111,435,684 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362111,111,881 - 111,152,135 (-)NCBINCBI36hg18NCBI36
Build 342111,111,642 - 111,151,895NCBI
Celera2105,046,046 - 105,086,323 (-)NCBI
Cytogenetic Map2q13NCBI
HuRef2104,274,404 - 104,314,815 (-)NCBIHuRef
CHM1_12111,399,569 - 111,439,978 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


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Genomics

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Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
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Additional Information

External Database Links
Nomenclature History
 
More on BUB1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1323304
Created: 2005-01-12
Species: Homo sapiens
Last Modified: 2020-01-14
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.