Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: FGD3 (FYVE, RhoGEF and PH domain containing 3) Homo sapiens
Symbol: FGD3
Name: FYVE, RhoGEF and PH domain containing 3
Description: Predicted to have guanyl-nucleotide exchange factor activity and small GTPase binding activity. Predicted to be involved in several processes, including filopodium assembly; regulation of GTPase activity; and regulation of cell shape. Predicted to localize to the Golgi apparatus; lamellipodium; and ruffle; INTERACTS WITH 17alpha-ethynylestradiol; 17beta-estradiol; aflatoxin B1.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: faciogenital dysplasia 3; FGD1 family, member 3; FLJ00004; FYVE, RhoGEF and PH domain-containing protein 3; MGC117260; ZFYVE5; zinc finger FYVE domain-containing protein 5
Mus musculus (house mouse) : Fgd3 (FYVE, RhoGEF and PH domain containing 3)  MGI  Alliance
Rattus norvegicus (Norway rat) : Fgd3 (FYVE, RhoGEF and PH domain containing 3)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Fgd3 (FYVE, RhoGEF and PH domain containing 3)
Pan paniscus (bonobo/pygmy chimpanzee) : FGD3 (FYVE, RhoGEF and PH domain containing 3)
Canis lupus familiaris (dog) : FGD3 (FYVE, RhoGEF and PH domain containing 3)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Fgd3 (FYVE, RhoGEF and PH domain containing 3)
Sus scrofa (pig) : FGD3 (FYVE, RhoGEF and PH domain containing 3)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38992,947,523 - 93,036,236 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37995,709,601 - 95,798,518 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36994,749,422 - 94,838,339 (+)NCBINCBI36hg18NCBI36
Celera966,151,416 - 66,240,262 (+)NCBI
Cytogenetic Map9q22.31NCBI
HuRef965,386,766 - 65,475,463 (+)NCBIHuRef
CHM1_1995,856,394 - 95,945,176 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status



Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
More on FGD3
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1323332
Created: 2005-01-12
Species: Homo sapiens
Last Modified: 2019-11-26
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.