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Gene: FGD3 (FYVE, RhoGEF and PH domain containing 3) Homo sapiens
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Symbol: FGD3
Name: FYVE, RhoGEF and PH domain containing 3
Description: Predicted to have guanyl-nucleotide exchange factor activity and small GTPase binding activity. Predicted to be involved in several processes, including filopodium assembly; regulation of GTPase activity; and regulation of cell shape. Predicted to localize to the Golgi apparatus; lamellipodium; and ruffle; INTERACTS WITH 17alpha-ethynylestradiol; 17beta-estradiol; aflatoxin B1.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: faciogenital dysplasia 3; FGD1 family, member 3; FLJ00004; FYVE, RhoGEF and PH domain-containing protein 3; MGC117260; ZFYVE5; zinc finger FYVE domain-containing protein 5
Orthologs:
Mus musculus (house mouse) : Fgd3 (FYVE, RhoGEF and PH domain containing 3)  MGI  Alliance
Rattus norvegicus (Norway rat) : Fgd3 (FYVE, RhoGEF and PH domain containing 3)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Fgd3 (FYVE, RhoGEF and PH domain containing 3)
Pan paniscus (bonobo/pygmy chimpanzee) : FGD3 (FYVE, RhoGEF and PH domain containing 3)
Canis lupus familiaris (dog) : FGD3 (FYVE, RhoGEF and PH domain containing 3)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Fgd3 (FYVE, RhoGEF and PH domain containing 3)
Sus scrofa (pig) : FGD3 (FYVE, RhoGEF and PH domain containing 3)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38992,947,523 - 93,036,236 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37995,709,601 - 95,798,518 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36994,749,422 - 94,838,339 (+)NCBINCBI36hg18NCBI36
Celera966,151,416 - 66,240,262 (+)NCBI
Cytogenetic Map9q22.31NCBI
HuRef965,386,766 - 65,475,463 (+)NCBIHuRef
CHM1_1995,856,394 - 95,945,176 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
 
More on FGD3
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1323332
Created: 2005-01-12
Species: Homo sapiens
Last Modified: 2019-11-26
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.