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Gene: Casp14 (caspase 14) Mus musculus
Symbol: Casp14
Name: caspase 14
CRRD ID: 1323415
Description: Predicted to have cysteine-type endopeptidase activity involved in execution phase of apoptosis. Predicted to be involved in cornification and proteolysis. Predicted to localize to several cellular components, including keratin filament; mitochondrion; and nucleoplasm. Is expressed in embryo; epidermis; epidermis stratum corneum; and skin. Human ortholog(s) of this gene implicated in autosomal recessive congenital ichthyosis. Orthologous to human CASP14 (caspase 14); INTERACTS WITH (+)-dexrazoxane; 1,2-dichloroethane; 1,2-dimethylhydrazine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: CASP-14; caspase-14; MGC123948; MGC123949; MIC; MICE; mini; mini-ICE
Homo sapiens (human) : CASP14 (caspase 14)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Casp14 (caspase 14)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Casp14 (caspase 14)
Pan paniscus (bonobo/pygmy chimpanzee) : CASP14 (caspase 14)
Canis lupus familiaris (dog) : CASP14 (caspase 14)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Casp14 (caspase 14)
Sus scrofa (pig) : CASP14 (caspase 14)
Chlorocebus sabaeus (African green monkey) : CASP14 (caspase 14)
Heterocephalus glaber (naked mole-rat) : Casp14 (caspase 14)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm391078,547,829 - 78,554,181 (-)NCBI
GRCm381078,711,995 - 78,718,347 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1078,711,991 - 78,718,294 (-)EnsemblGRCm38mm10GRCm38
MGSCv371078,174,740 - 78,181,038 (-)NCBIGRCm37mm9NCBIm37
MGSCv361078,115,126 - 78,121,371 (-)NCBImm8
Celera1079,733,914 - 79,740,355 (-)NCBICelera
Cytogenetic Map10C1NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Casp14
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1323415
Created: 2005-01-12
Species: Mus musculus
Last Modified: 2020-10-13
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.