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Gene: PIDD1 (p53-induced death domain protein 1) Homo sapiens
Symbol: PIDD1
Name: p53-induced death domain protein 1
Description: Exhibits endopeptidase activity. Involved in several processes, including DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest; protein autoprocessing; and regulation of apoptotic process. Localizes to Golgi apparatus; cytosol; and nucleus.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: DKFZp434D229; leucine-rich and death domain containing; leucine-rich repeat and death domain-containing protein; leucine-rich repeats and death domain containing; LRDD; MGC16925; p53-induced death domain-containing protein 1; p53-induced protein with a death domain; PIDD
Mus musculus (house mouse) : Pidd1 (p53 induced death domain protein 1)  MGI  Alliance
Rattus norvegicus (Norway rat) : Pidd1 (p53-induced death domain protein 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Pidd1 (p53-induced death domain protein 1)
Pan paniscus (bonobo/pygmy chimpanzee) : PIDD1 (p53-induced death domain protein 1)
Canis lupus familiaris (dog) : PIDD1 (p53-induced death domain protein 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Pidd1 (p53-induced death domain protein 1)
Sus scrofa (pig) : PIDD1 (p53-induced death domain protein 1)
Chlorocebus sabaeus (African green monkey) : PIDD1 (p53-induced death domain protein 1)
Heterocephalus glaber (naked mole-rat) : Pidd1 (p53-induced death domain protein 1)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38 Ensembl11799,179 - 809,753 (-)EnsemblGRCh38hg38GRCh38
GRCh3811799,179 - 809,867 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh3711799,179 - 809,872 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 3611789,179 - 795,245 (-)NCBINCBI36hg18NCBI36
Build 3411789,178 - 794,464NCBI
Celera11865,757 - 871,046 (-)NCBI
Cytogenetic Map11p15.5NCBI
HuRef11615,945 - 621,235 (-)NCBIHuRef
CHM1_111798,086 - 804,157 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on PIDD1
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1323429
Created: 2005-01-12
Species: Homo sapiens
Last Modified: 2020-05-05
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.