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Gene: POLR3D (RNA polymerase III subunit D) Homo sapiens
Symbol: POLR3D
Name: RNA polymerase III subunit D
Description: Predicted to have DNA binding activity; DNA-directed 5'-3' RNA polymerase activity; and chromatin binding activity. Involved in positive regulation of innate immune response and positive regulation of interferon-beta production. Localizes to RNA polymerase III complex; cytosol; and nuclear speck. Colocalizes with nuclear chromatin.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: BN51 (BHK21) temperature sensitivity complementing; BN51T; C53; DNA-directed RNA polymerase III 47 kDa polypeptide; DNA-directed RNA polymerase III subunit D; DNA-directed RNA polymerase III subunit RPC4; polymerase (RNA) III (DNA directed) polypeptide D, 44kDa; polymerase (RNA) III subunit D; RNA polymerase III 47 kDa subunit; RNA polymerase III subunit C4; RPC4; RPC53; RPC53 homolog; temperature sensitive complementation, cell cycle specific, tsBN51; TSBN51
Mus musculus (house mouse) : Polr3d (polymerase (RNA) III (DNA directed) polypeptide D)  MGI  Alliance
Rattus norvegicus (Norway rat) : Polr3d (RNA polymerase III subunit D)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Polr3d (RNA polymerase III subunit D)
Pan paniscus (bonobo/pygmy chimpanzee) : POLR3D (RNA polymerase III subunit D)
Canis lupus familiaris (dog) : POLR3D (RNA polymerase III subunit D)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Polr3d (RNA polymerase III subunit D)
Sus scrofa (pig) : POLR3D (RNA polymerase III subunit D)
Chlorocebus sabaeus (African green monkey) : POLR3D (RNA polymerase III subunit D)
Heterocephalus glaber (naked mole-rat) : Polr3d (RNA polymerase III subunit D)
more info ...
Related Pseudogenes: POLR3DP1  
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38.p13 Ensembl822,245,133 - 22,254,601 (+)EnsemblGRCh38hg38GRCh38
GRCh38822,245,104 - 22,254,601 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37822,102,619 - 22,108,680 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36822,158,564 - 22,164,625 (+)NCBINCBI36hg18NCBI36
Build 34822,158,563 - 22,164,624NCBI
Celera821,064,952 - 21,071,014 (+)NCBI
Cytogenetic Map8p21.3NCBI
HuRef820,644,813 - 20,650,874 (+)NCBIHuRef
CHM1_1822,304,282 - 22,310,343 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on POLR3D
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1323468
Created: 2005-01-12
Species: Homo sapiens
Last Modified: 2020-09-08
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.