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Gene: GPR65 (G protein-coupled receptor 65) Homo sapiens
Symbol: GPR65
Name: G protein-coupled receptor 65
Description: Exhibits G protein-coupled receptor activity. Involved in several processes, including actin cytoskeleton reorganization; activation of GTPase activity; and positive regulation of stress fiber assembly. Localizes to the plasma membrane; INTERACTS WITH 3,3',4,4'-tetrachlorobiphenyl; aflatoxin B1; antirheumatic drug.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: G-protein coupled receptor 65; hTDAG8; psychosine receptor; T-cell death-associated gene 8 protein; TDAG8
Mus musculus (house mouse) : Gpr65 (G-protein coupled receptor 65)  MGI  Alliance
Rattus norvegicus (Norway rat) : Gpr65 (G-protein coupled receptor 65)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Gpr65 (G protein-coupled receptor 65)
Pan paniscus (bonobo/pygmy chimpanzee) : GPR65 (G protein-coupled receptor 65)
Canis lupus familiaris (dog) : GPR65 (G protein-coupled receptor 65)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Gpr65 (G protein-coupled receptor 65)
Sus scrofa (pig) : GPR65 (G protein-coupled receptor 65)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh381488,005,135 - 88,014,811 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371488,471,468 - 88,481,155 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361487,541,249 - 87,548,168 (+)NCBINCBI36hg18NCBI36
Build 341487,541,248 - 87,548,167NCBI
Celera1468,517,156 - 68,526,848 (+)NCBI
Cytogenetic Map14q31.3NCBI
HuRef1468,641,596 - 68,651,288 (+)NCBIHuRef
CHM1_11488,409,597 - 88,419,284 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status



Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
More on GPR65
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1323495
Created: 2005-01-12
Species: Homo sapiens
Last Modified: 2019-10-16
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.