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Gene: Laptm4b (lysosomal-associated protein transmembrane 4B) Mus musculus
Symbol: Laptm4b
Name: lysosomal-associated protein transmembrane 4B
Description: Predicted to have ceramide binding activity; enzyme binding activity; and phosphatidylinositol bisphosphate binding activity. Predicted to be involved in several processes, including negative regulation of lysosomal protein catabolic process; negative regulation of transforming growth factor beta1 production; and regulation of lysosomal membrane permeability. Predicted to localize to several cellular components, including the cell projection; endosome; and lysosomal membrane. Is expressed in several structures, including central nervous system; incisor; liver; retina; and submandibular gland primordium. Orthologous to human LAPTM4B (lysosomal protein transmembrane 4 beta); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 3,4-methylenedioxymethamphetamine; 4,4'-diaminodiphenylmethane.
Type: protein-coding
Also known as: C330023P13Rik; LAPTM4beta; lysosomal-associated transmembrane protein 4; lysosomal-associated transmembrane protein 4B
Homo sapiens (human) : LAPTM4B (lysosomal protein transmembrane 4 beta)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Laptm4b (lysosomal protein transmembrane 4 beta)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Laptm4b (lysosomal protein transmembrane 4 beta)
Pan paniscus (bonobo/pygmy chimpanzee) : LAPTM4B (lysosomal protein transmembrane 4 beta)
Canis lupus familiaris (dog) : LAPTM4B (lysosomal protein transmembrane 4 beta)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Laptm4b (lysosomal protein transmembrane 4 beta)
Sus scrofa (pig) : LAPTM4B (lysosomal protein transmembrane 4 beta)
Chlorocebus sabaeus (African green monkey) : LAPTM4B (lysosomal protein transmembrane 4 beta)
Heterocephalus glaber (naked mole-rat) : Laptm4b (lysosomal protein transmembrane 4 beta)
more info ...
Related Pseudogenes: Gm18963  
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38 Ensembl1534,238,028 - 34,284,302 (+)EnsemblGRCm38mm10GRCm38
GRCm381534,238,026 - 34,284,295 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371534,167,781 - 34,214,050 (+)NCBIGRCm37mm9NCBIm37
MGSCv361534,182,615 - 34,228,884 (+)NCBImm8
Celera1534,858,574 - 34,904,967 (+)NCBICelera
Cytogenetic Map15B3.1NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Laptm4b
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1323528
Created: 2005-01-12
Species: Mus musculus
Last Modified: 2020-03-25
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.