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Gene: Laptm4b (lysosomal-associated protein transmembrane 4B) Mus musculus
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Symbol: Laptm4b
Name: lysosomal-associated protein transmembrane 4B
Description: Predicted to have ceramide binding activity; enzyme binding activity; and phosphatidylinositol bisphosphate binding activity. Predicted to be involved in several processes, including negative regulation of lysosomal protein catabolic process; negative regulation of transforming growth factor beta1 production; and regulation of lysosomal membrane permeability. Predicted to localize to several cellular components, including the cell projection; endosome; and lysosomal membrane. Is expressed in several structures, including central nervous system; incisor; liver; retina; and submandibular gland primordium. Orthologous to human LAPTM4B (lysosomal protein transmembrane 4 beta); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 3,4-methylenedioxymethamphetamine; 4,4'-diaminodiphenylmethane.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: C330023P13Rik; LAPTM4beta; lysosomal-associated transmembrane protein 4; lysosomal-associated transmembrane protein 4B
Orthologs:
Homo sapiens (human) : LAPTM4B (lysosomal protein transmembrane 4 beta)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Laptm4b (lysosomal protein transmembrane 4 beta)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Laptm4b (lysosomal protein transmembrane 4 beta)
Pan paniscus (bonobo/pygmy chimpanzee) : LAPTM4B (lysosomal protein transmembrane 4 beta)
Canis lupus familiaris (dog) : LAPTM4B (lysosomal protein transmembrane 4 beta)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Laptm4b (lysosomal protein transmembrane 4 beta)
Sus scrofa (pig) : LAPTM4B (lysosomal protein transmembrane 4 beta)
Chlorocebus sabaeus (African green monkey) : LAPTM4B (lysosomal protein transmembrane 4 beta)
Heterocephalus glaber (naked mole-rat) : Laptm4b (lysosomal protein transmembrane 4 beta)
more info ...
Related Pseudogenes: Gm18963  
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38 Ensembl1534,238,028 - 34,284,302 (+)EnsemblGRCm38mm10GRCm38
GRCm381534,238,026 - 34,284,295 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371534,167,781 - 34,214,050 (+)NCBIGRCm37mm9NCBIm37
MGSCv361534,182,615 - 34,228,884 (+)NCBImm8
Celera1534,858,574 - 34,904,967 (+)NCBICelera
Cytogenetic Map15B3.1NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Laptm4b
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1323528
Created: 2005-01-12
Species: Mus musculus
Last Modified: 2020-03-25
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.