Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: Mtmr2 (myotubularin related protein 2) Mus musculus
Analyze
Symbol: Mtmr2
Name: myotubularin related protein 2
Description: Exhibits identical protein binding activity and phosphatidylinositol phosphate phosphatase activity. Involved in dephosphorylation; negative regulation of myelination; and nervous system development. Localizes to vacuolar membrane. Used to study Charcot-Marie-Tooth disease type 4B1. Human ortholog(s) of this gene implicated in Charcot-Marie-Tooth disease type 4B1. Is expressed in several structures, including eye; genitourinary system; gut; immune system; and nervous system. Orthologous to human MTMR2 (myotubularin related protein 2); PARTICIPATES IN fructose and mannose metabolic pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; ethanol; methotrexate.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 6030445P13Rik; myotubularin-related protein 2; phosphatidylinositol-3,5-bisphosphate 3-phosphatase; phosphatidylinositol-3-phosphate phosphatase
Orthologs:
Homo sapiens (human) : MTMR2 (myotubularin related protein 2)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Mtmr2 (myotubularin related protein 2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Mtmr2 (myotubularin related protein 2)
Pan paniscus (bonobo/pygmy chimpanzee) : MTMR2 (myotubularin related protein 2)
Canis lupus familiaris (dog) : MTMR2 (myotubularin related protein 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Mtmr2 (myotubularin related protein 2)
Sus scrofa (pig) : MTMR2 (myotubularin related protein 2)
Chlorocebus sabaeus (African green monkey) : MTMR2 (myotubularin related protein 2)
Heterocephalus glaber (naked mole-rat) : Mtmr2 (myotubularin related protein 2)
more info ...
Related Pseudogenes: Gm4880   Gm5997   Gm8314  
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38 Ensembl913,748,410 - 13,806,481 (+)EnsemblGRCm38mm10GRCm38
GRCm38913,747,260 - 13,808,896 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37913,553,625 - 13,610,925 (+)NCBIGRCm37mm9NCBIm37
MGSCv36913,498,807 - 13,556,194 (+)NCBImm8
Celera911,027,704 - 11,084,917 (+)NCBICelera
Cytogenetic Map9A1NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Mtmr2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1323546
Created: 2005-01-12
Species: Mus musculus
Last Modified: 2020-03-25
Status: ACTIVE



NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.