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Gene: Mtmr2 (myotubularin related protein 2) Mus musculus
Symbol: Mtmr2
Name: myotubularin related protein 2
Description: Exhibits identical protein binding activity and phosphatidylinositol phosphate phosphatase activity. Involved in dephosphorylation; negative regulation of myelination; and nervous system development. Localizes to vacuolar membrane. Used to study Charcot-Marie-Tooth disease type 4B1. Human ortholog(s) of this gene implicated in Charcot-Marie-Tooth disease type 4B1. Is expressed in several structures, including eye; genitourinary system; gut; immune system; and nervous system. Orthologous to human MTMR2 (myotubularin related protein 2); PARTICIPATES IN fructose and mannose metabolic pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; ethanol; methotrexate.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 6030445P13Rik; myotubularin-related protein 2; phosphatidylinositol-3,5-bisphosphate 3-phosphatase; phosphatidylinositol-3-phosphate phosphatase
Homo sapiens (human) : MTMR2 (myotubularin related protein 2)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Mtmr2 (myotubularin related protein 2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Mtmr2 (myotubularin related protein 2)
Pan paniscus (bonobo/pygmy chimpanzee) : MTMR2 (myotubularin related protein 2)
Canis lupus familiaris (dog) : MTMR2 (myotubularin related protein 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Mtmr2 (myotubularin related protein 2)
Sus scrofa (pig) : MTMR2 (myotubularin related protein 2)
Chlorocebus sabaeus (African green monkey) : MTMR2 (myotubularin related protein 2)
Heterocephalus glaber (naked mole-rat) : Mtmr2 (myotubularin related protein 2)
more info ...
Related Pseudogenes: Gm4880   Gm5997   Gm8314  
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38 Ensembl913,748,410 - 13,806,481 (+)EnsemblGRCm38mm10GRCm38
GRCm38913,747,260 - 13,808,896 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37913,553,625 - 13,610,925 (+)NCBIGRCm37mm9NCBIm37
MGSCv36913,498,807 - 13,556,194 (+)NCBImm8
Celera911,027,704 - 11,084,917 (+)NCBICelera
Cytogenetic Map9A1NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Mtmr2
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1323546
Created: 2005-01-12
Species: Mus musculus
Last Modified: 2020-03-25
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.