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Gene: TWF1 (twinfilin actin binding protein 1) Homo sapiens
Symbol: TWF1
Name: twinfilin actin binding protein 1
CRRD ID: 1323555
Description: Exhibits ATP binding activity and actin binding activity. Involved in regulation of actin phosphorylation. Localizes to cytosol. Predicted to colocalize with ruffle membrane.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: A6; A6 protein tyrosine kinase; MGC23788; MGC41876; protein tyrosine kinase 9; PTK9; PTK9 protein tyrosine kinase 9; twinfilin actin-binding protein 1; twinfilin, actin-binding protein, homolog 1; twinfilin-1
Mus musculus (house mouse) : Twf1 (twinfilin actin binding protein 1)  MGI  Alliance
Rattus norvegicus (Norway rat) : Twf1 (twinfilin actin-binding protein 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Twf1 (twinfilin actin binding protein 1)
Pan paniscus (bonobo/pygmy chimpanzee) : TWF1 (twinfilin actin binding protein 1)
Canis lupus familiaris (dog) : TWF1 (twinfilin actin binding protein 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Twf1 (twinfilin actin binding protein 1)
Sus scrofa (pig) : TWF1 (twinfilin actin binding protein 1)
Chlorocebus sabaeus (African green monkey) : TWF1 (twinfilin actin binding protein 1)
Heterocephalus glaber (naked mole-rat) : Twf1 (twinfilin actin binding protein 1)
more info ...
Related Pseudogenes: TWF1P1   TWF1P2  
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38.p13 Ensembl1243,793,723 - 43,806,328 (-)EnsemblGRCh38hg38GRCh38
GRCh38.p13 Ensembl1243,793,723 - 43,806,375 (-)EnsemblGRCh38hg38GRCh38
GRCh381243,793,723 - 43,806,317 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh371244,187,526 - 44,200,178 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361242,473,793 - 42,486,445 (-)NCBINCBI36hg18NCBI36
Celera1242,989,914 - 43,003,516 (-)NCBI
Cytogenetic Map12q12NCBI
HuRef1241,215,942 - 41,228,787 (-)NCBIHuRef
CHM1_11244,152,507 - 44,165,159 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on TWF1
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1323555
Created: 2005-01-12
Species: Homo sapiens
Last Modified: 2020-09-16
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.