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Gene: IQGAP1 (IQ motif containing GTPase activating protein 1) Homo sapiens
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Symbol: IQGAP1
Name: IQ motif containing GTPase activating protein 1
Description: Exhibits several functions, including S100 protein binding activity; calmodulin binding activity; and enzyme binding activity. Involved in several processes, including cellular response to calcium ion; cellular response to epidermal growth factor stimulus; and neuron projection extension. Localizes to several cellular components, including the extrinsic component of cytoplasmic side of plasma membrane; midbody; and ruffle. Predicted to colocalize with the actin cytoskeleton and microtubule cytoskeleton.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: HUMORFA01; KIAA0051; p195; ras GTPase-activating-like protein IQGAP1; RasGAP-like with IQ motifs; SAR1
Orthologs:
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381590,388,242 - 90,502,239 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371590,931,473 - 91,045,475 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361588,732,477 - 88,846,479 (+)NCBINCBI36hg18NCBI36
Build 341588,732,476 - 88,846,479NCBI
Celera1567,336,216 - 67,450,214 (+)NCBI
Cytogenetic Map15q26.1NCBI
HuRef1567,043,721 - 67,156,752 (+)NCBIHuRef
CHM1_11590,773,219 - 90,887,196 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


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Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
 
More on IQGAP1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1323573
Created: 2005-01-12
Species: Homo sapiens
Last Modified: 2019-11-05
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.