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Gene: Bap1 (Brca1 associated protein 1) Mus musculus
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Symbol: Bap1
Name: Brca1 associated protein 1
Description: Predicted to have chromatin binding activity and thiol-dependent ubiquitin-specific protease activity. Involved in macrophage homeostasis; regulation of cytokine production involved in inflammatory response; and response to inorganic substance. Predicted to localize to the PR-DUB complex; cytosol; and nucleoplasm. Used to study myelodysplastic syndrome. Human ortholog(s) of this gene implicated in basal cell carcinoma. Is expressed in gonad and mammary gland. Orthologous to human BAP1 (BRCA1 associated protein 1); PARTICIPATES IN histone modification pathway; INTERACTS WITH (S)-nicotine; 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 2300006C11Rik; AA989761; AW553466; BRCA1-associated protein 1; mKIAA0272; ubiquitin C-terminal hydrolase X4; ubiquitin carboxyl-terminal hydrolase BAP1; uch-x4
Orthologs:
Homo sapiens (human) : BAP1 (BRCA1 associated protein 1)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Bap1 (Brca1 associated protein 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Bap1 (BRCA1 associated protein 1)
Pan paniscus (bonobo/pygmy chimpanzee) : BAP1 (BRCA1 associated protein 1)
Canis lupus familiaris (dog) : BAP1 (BRCA1 associated protein 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Bap1 (BRCA1 associated protein 1)
Sus scrofa (pig) : BAP1 (BRCA1 associated protein 1)
more info ...
Related Pseudogenes: Gm18332  
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm381431,251,352 - 31,259,930 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371432,064,675 - 32,073,115 (+)NCBIGRCm37mm9NCBIm37
MGSCv361430,080,596 - 30,088,939 (+)NCBImm8
Celera1427,510,099 - 27,518,539 (+)NCBICelera
Cytogenetic Map14 BNCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Bap1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1323653
Created: 2005-01-12
Species: Mus musculus
Last Modified: 2019-09-12
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.