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Gene: HLX (H2.0 like homeobox) Homo sapiens
Symbol: HLX
Name: H2.0 like homeobox
Description: Exhibits sequence-specific DNA binding activity. Predicted to be involved in animal organ development. Predicted to localize to nuclear chromatin; PARTICIPATES IN interleukin-12 signaling pathway; INTERACTS WITH 17beta-estradiol; 3-isobutyl-1-methyl-7H-xanthine; 4,4'-sulfonyldiphenol.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: H2.0-like homeo box 1; h2.0-like homeo box 1 (drosophila); H2.0-like homeo box-1; H2.0-like homeobox; H2.0-like homeobox 1; H2.0-like homeobox protein; HB24; HLX1; homeobox protein HB24; homeobox protein HLX1
Mus musculus (house mouse) : Hlx (H2.0-like homeobox)  MGI  Alliance
Rattus norvegicus (Norway rat) : Hlx (H2.0-like homeobox)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Hlx (H2.0 like homeobox)
Pan paniscus (bonobo/pygmy chimpanzee) : HLX (H2.0 like homeobox)
Canis lupus familiaris (dog) : HLX (H2.0 like homeobox)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Hlx (H2.0 like homeobox)
Sus scrofa (pig) : HLX (H2.0 like homeobox)
Chlorocebus sabaeus (African green monkey) : HLX (H2.0 like homeobox)
Heterocephalus glaber (naked mole-rat) : Hlx (H2.0 like homeobox)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38.p13 Ensembl1220,879,431 - 220,885,059 (+)EnsemblGRCh38hg38GRCh38
GRCh381220,879,443 - 220,885,059 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371221,052,743 - 221,058,401 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361219,119,382 - 219,125,018 (+)NCBINCBI36hg18NCBI36
Build 341217,441,153 - 217,446,790NCBI
Celera1194,272,144 - 194,277,780 (+)NCBI
Cytogenetic Map1q41NCBI
HuRef1191,727,277 - 191,732,908 (+)NCBIHuRef
CHM1_11222,325,244 - 222,330,902 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on HLX
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1323685
Created: 2005-01-12
Species: Homo sapiens
Last Modified: 2020-07-28
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.