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Gene: Ptgdr2 (prostaglandin D2 receptor 2) Mus musculus
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Symbol: Ptgdr2
Name: prostaglandin D2 receptor 2
Description: Exhibits prostaglandin D receptor activity; prostaglandin F receptor activity; and prostaglandin J receptor activity. Involved in several processes, including adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway; negative regulation of male germ cell proliferation; and positive regulation of G protein-coupled receptor signaling pathway. Predicted to localize to the integral component of plasma membrane. Human ortholog(s) of this gene implicated in asthma. Orthologous to human PTGDR2 (prostaglandin D2 receptor 2); INTERACTS WITH 13,14-dihydro-15-ketoprostaglandin D2; 15-deoxy-Delta(12,14)-prostaglandin J2; 3',5'-cyclic AMP.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: chemoattractant receptor-homologous molecule expressed on TH2 cells; Crth2; G protein-coupled receptor 44; G-protein coupled receptor 44; Gpr44; Grp45; MGC130436; PGD2 receptor; prostaglandin D2 receptor CRTH2; putative G-protein coupled receptor 44
Orthologs:
Homo sapiens (human) : PTGDR2 (prostaglandin D2 receptor 2)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Ptgdr2 (prostaglandin D2 receptor 2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Ptgdr2 (prostaglandin D2 receptor 2)
Pan paniscus (bonobo/pygmy chimpanzee) : PTGDR2 (prostaglandin D2 receptor 2)
Canis lupus familiaris (dog) : PTGDR2 (prostaglandin D2 receptor 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Ptgdr2 (prostaglandin D2 receptor 2)
Sus scrofa (pig) : PTGDR2 (prostaglandin D2 receptor 2)
Chlorocebus sabaeus (African green monkey) : PTGDR2 (prostaglandin D2 receptor 2)
Heterocephalus glaber (naked mole-rat) : Ptgdr2 (prostaglandin D2 receptor 2)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38 Ensembl1910,937,160 - 10,942,511 (+)Ensembl
GRCm381910,924,519 - 10,942,511 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371911,011,650 - 11,017,001 (+)NCBIGRCm37mm9NCBIm37
MGSCv361911,004,205 - 11,009,556 (+)NCBImm8
Celera1911,630,059 - 11,635,420 (+)NCBICelera
Cytogenetic Map19 ANCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
Nomenclature History
 
More on Ptgdr2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1323731
Created: 2005-01-12
Species: Mus musculus
Last Modified: 2019-12-25
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.