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Gene: STK4 (serine/threonine kinase 4) Homo sapiens
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Symbol: STK4
Name: serine/threonine kinase 4
Description: Exhibits several functions, including ATP binding activity; magnesium ion binding activity; and protein homodimerization activity. Involved in several processes, including hippo signaling; protein phosphorylation; and protein stabilization. Localizes to the cytosol; nuclear body; and protein-containing complex.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: dJ211D12.2 (serine/threonine kinase 4 (MST1, KRS2)); DKFZp686A2068; kinase responsive to stress 2; KRS2; mammalian STE20-like protein kinase 1; mammalian sterile 20-like 1; MST-1; MST1; serine/threonine-protein kinase 4; serine/threonine-protein kinase Krs-2; STE20-like kinase MST1; TIIAC; yeast Ste20-like; YSK3
Orthologs:
Mus musculus (house mouse) : Stk4 (serine/threonine kinase 4)  MGI  Alliance
Rattus norvegicus (Norway rat) : Stk4 (serine/threonine kinase 4)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Stk4 (serine/threonine kinase 4)
Pan paniscus (bonobo/pygmy chimpanzee) : STK4 (serine/threonine kinase 4)
Canis lupus familiaris (dog) : STK4 (serine/threonine kinase 4)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Stk4 (serine/threonine kinase 4)
Sus scrofa (pig) : STK4 (serine/threonine kinase 4)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
NCBI Annotation Information: Note: MST1 (Gene ID: 4485) and STK4 (Gene ID: 6789) share the MST1 symbol/alias in common. MST1 is a widely used alternative name for serine/threonine kinase 4 (STK4), which can be confused with the official symbol for macrophage stimulating 1 (MST1). [01 Jun 2018]
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382044,966,470 - 45,080,021 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh372043,595,120 - 43,708,600 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362043,028,534 - 43,142,008 (+)NCBINCBI36hg18NCBI36
Build 342043,028,533 - 43,142,005NCBI
Celera2040,303,755 - 40,417,237 (+)NCBI
Cytogenetic Map20q13.12NCBI
HuRef2040,336,825 - 40,450,492 (+)NCBIHuRef
CHM1_12043,497,895 - 43,611,365 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
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Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
 
More on STK4
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1323808
Created: 2005-01-12
Species: Homo sapiens
Last Modified: 2019-11-26
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.