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Gene: HES6 (hes family bHLH transcription factor 6) Homo sapiens
Symbol: HES6
Name: hes family bHLH transcription factor 6
Description: Predicted to have DNA-binding transcription repressor activity, RNA polymerase II-specific; RNA polymerase II regulatory region sequence-specific DNA binding activity; and transcription coregulator activity. Predicted to be involved in anterior/posterior pattern specification; negative regulation of transcription by RNA polymerase II; and regulation of neurogenesis. Predicted to localize to the nuclear chromatin and transcription factor complex.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: bHLHb41; bHLHc23; C-HAIRY1; class B basic helix-loop-helix protein 41; hairy and enhancer of split 6; HES-6; transcription cofactor HES-6
Mus musculus (house mouse) : Hes6 (hairy and enhancer of split 6)  MGI  Alliance
Rattus norvegicus (Norway rat) : Hes6 (hes family bHLH transcription factor 6)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Hes6 (hes family bHLH transcription factor 6)
Pan paniscus (bonobo/pygmy chimpanzee) : HES6 (hes family bHLH transcription factor 6)
Canis lupus familiaris (dog) : HES6 (hes family bHLH transcription factor 6)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Hes6 (hes family bHLH transcription factor 6)
Sus scrofa (pig) : HES6 (hes family bHLH transcription factor 6)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh382238,238,267 - 238,240,038 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh372239,146,908 - 239,148,681 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362238,811,647 - 238,813,409 (-)NCBINCBI36hg18NCBI36
Build 342238,928,909 - 238,930,670NCBI
Celera2232,859,462 - 232,861,235 (-)NCBI
Cytogenetic Map2q37.3NCBI
HuRef2230,937,958 - 230,939,843 (-)NCBIHuRef
CHM1_12239,152,761 - 239,154,618 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status



Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on HES6
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1323828
Created: 2005-01-12
Species: Homo sapiens
Last Modified: 2019-10-16
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.