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Gene: Hes6 (hairy and enhancer of split 6) Mus musculus
Symbol: Hes6
Name: hairy and enhancer of split 6
Description: Exhibits DNA-binding transcription repressor activity, RNA polymerase II-specific; RNA polymerase II regulatory region sequence-specific DNA binding activity; and transcription coregulator activity. Involved in cell differentiation; negative regulation of transcription by RNA polymerase II; and nervous system development. Localizes to the transcription factor complex. Is expressed in several structures, including alimentary system; central nervous system; embryo mesenchyme; genitourinary system; and sensory organ. Orthologous to human HES6 (hes family bHLH transcription factor 6); INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine; 2-butoxyethanol.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: AI326893; bHLHb41; transcription cofactor HES-6
Homo sapiens (human) : HES6 (hes family bHLH transcription factor 6)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Hes6 (hes family bHLH transcription factor 6)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Hes6 (hes family bHLH transcription factor 6)
Pan paniscus (bonobo/pygmy chimpanzee) : HES6 (hes family bHLH transcription factor 6)
Canis lupus familiaris (dog) : HES6 (hes family bHLH transcription factor 6)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Hes6 (hes family bHLH transcription factor 6)
Sus scrofa (pig) : HES6 (hes family bHLH transcription factor 6)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38191,411,483 - 91,414,038 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37193,308,060 - 93,309,799 (-)NCBIGRCm37mm9NCBIm37
MGSCv36193,241,889 - 93,243,628 (-)NCBImm8
Celera194,348,702 - 94,350,441 (-)NCBICelera
Cytogenetic Map1 DNCBI
JBrowse: View Region in Genome Browser (JBrowse)

Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
Nomenclature History
More on Hes6
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1323829
Created: 2005-01-12
Species: Mus musculus
Last Modified: 2019-11-27
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.