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Gene: Sdhaf2 (succinate dehydrogenase complex assembly factor 2) Mus musculus
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Symbol: Sdhaf2
Name: succinate dehydrogenase complex assembly factor 2
Description: Involved in negative regulation of canonical Wnt signaling pathway; negative regulation of epithelial to mesenchymal transition; and protein dephosphorylation. Localizes to the mitochondrion. Human ortholog(s) of this gene implicated in paraganglioma. Orthologous to human SDHAF2 (succinate dehydrogenase complex assembly factor 2); INTERACTS WITH 2,2',4,4'-Tetrabromodiphenyl ether; benzo[a]pyrene; cadmium atom.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 0610038F07Rik; AA407634; AW049997; MGC61338; SDH assembly factor 2; succinate dehydrogenase assembly factor 2, mitochondrial; succinate dehydrogenase subunit 5, mitochondrial
Orthologs:
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm381910,500,512 - 10,525,209 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371910,575,002 - 10,599,699 (-)NCBIGRCm37mm9NCBIm37
MGSCv361910,568,685 - 10,592,254 (-)NCBImm8
Celera1911,196,361 - 11,220,981 (-)NCBICelera
Cytogenetic Map19 ANCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Sdhaf2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1331887
Created: 2005-02-01
Species: Mus musculus
Last Modified: 2019-11-27
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.