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Gene: Aldh1a1 (aldehyde dehydrogenase family 1, subfamily A1) Mus musculus
Symbol: Aldh1a1
Name: aldehyde dehydrogenase family 1, subfamily A1
Description: Exhibits 3-chloroallyl aldehyde dehydrogenase activity. Involved in several processes, including negative regulation of cold-induced thermogenesis; optic cup morphogenesis involved in camera-type eye development; and retinoid metabolic process. Predicted to localize to the cytosol and nucleus. Is expressed in several structures, including alimentary system; genitourinary system; nervous system; respiratory system; and sensory organ. Orthologous to human ALDH1A1 (aldehyde dehydrogenase 1 family member A1); PARTICIPATES IN cyclophosphamide pharmacodynamics pathway; cyclophosphamide pharmacokinetics pathway; ifosfamide pharmacodynamics pathway; INTERACTS WITH (S)-nicotine; 1,1-dichloroethene; 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: Ahd-2; Ahd2; alcohol dehydrogenase family 1, subfamily A1; alcohol dehydrogenase family 1, subfamily A2; aldehyde dehydrogenase 1, liver cytosolic (class 1); aldehyde dehydrogenase family 1 member A1; aldehyde dehydrogenase, cytosolic; ALDH-E1; Aldh1; Aldh1a2; ALHDII; E1; RALDH 1; Raldh1; retinal dehydrogenase 1
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38 Ensembl1920,492,715 - 20,643,465 (+)Ensembl
GRCm381920,492,583 - 20,643,463 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371920,676,472 - 20,717,952 (+)NCBIGRCm37mm9NCBIm37
MGSCv361920,669,079 - 20,710,559 (+)NCBImm8
Celera1921,323,202 - 21,366,435 (+)NCBICelera
Cytogenetic Map19 BNCBI
cM Map1913.91NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Aldh1a1
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1332089
Created: 2005-02-01
Species: Mus musculus
Last Modified: 2019-11-27
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.