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Gene: Socs2 (suppressor of cytokine signaling 2) Mus musculus
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Symbol: Socs2
Name: suppressor of cytokine signaling 2
Description: Exhibits growth hormone receptor binding activity. Involved in several processes, including mammary gland development; negative regulation of growth; and negative regulation of receptor signaling pathway via JAK-STAT. Predicted to localize to the phosphatidylinositol 3-kinase complex. Human ortholog(s) of this gene implicated in endometrial cancer and ovarian carcinoma. Is expressed in Sertoli cell; embryo; and primary sex cord. Orthologous to human SOCS2 (suppressor of cytokine signaling 2); PARTICIPATES IN interleukin-2 signaling pathway; insulin signaling pathway; Jak-Stat signaling pathway; INTERACTS WITH 17beta-estradiol; 2,2',4,4',5,5'-hexachlorobiphenyl; 2,2',5,5'-tetrachlorobiphenyl.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 8030460M17; AI527257; AW108012; CIS-2; CIS2; Cish2; cytokine inducible SH2-containing protein 2; cytokine-inducible SH2 protein 2; D130043N08Rik; hg; JAB; MGC118106; SOCS-2; SSI-2; STAT-induced STAT inhibitor 2
Orthologs:
Homo sapiens (human) : SOCS2 (suppressor of cytokine signaling 2)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Socs2 (suppressor of cytokine signaling 2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Socs2 (suppressor of cytokine signaling 2)
Pan paniscus (bonobo/pygmy chimpanzee) : SOCS2 (suppressor of cytokine signaling 2)
Canis lupus familiaris (dog) : SOCS2 (suppressor of cytokine signaling 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Socs2 (suppressor of cytokine signaling 2)
Sus scrofa (pig) : SOCS2 (suppressor of cytokine signaling 2)
more info ...
Related Pseudogenes: Gm9847  
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm381095,383,903 - 95,417,321 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371094,874,124 - 94,879,491 (-)NCBIGRCm37mm9NCBIm37
MGSCv361094,841,730 - 94,846,509 (-)NCBImm8
Celera1097,386,894 - 97,392,261 (-)NCBICelera
Cytogenetic Map10 C2NCBI
cM Map1049.35NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
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Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
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Additional Information

External Database Links
 
More on Socs2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1332166
Created: 2005-02-01
Species: Mus musculus
Last Modified: 2019-11-27
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.