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Gene: Scn3b (sodium channel, voltage-gated, type III, beta) Mus musculus
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Symbol: Scn3b
Name: sodium channel, voltage-gated, type III, beta
Description: Exhibits ion channel binding activity and voltage-gated sodium channel activity involved in cardiac muscle cell action potential. Involved in cardiac muscle cell action potential; positive regulation of heart rate; and regulation of atrial cardiac muscle cell membrane depolarization. Localizes to the Z disc. Used to study Brugada syndrome 7. Human ortholog(s) of this gene implicated in Brugada syndrome 7. Is expressed in several structures, including gut; nervous system; sensory organ; skeletal musculature; and urinary system. Orthologous to human SCN3B (sodium voltage-gated channel beta subunit 3); INTERACTS WITH 3,4-methylenedioxymethamphetamine; arsane; arsenic atom.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 1110001K16Rik; 4833414B02Rik; brain and heart sodium channel beta 3 subunit; Scnb3; sodium channel subunit beta-3
Orthologs:
Homo sapiens (human) : SCN3B (sodium voltage-gated channel beta subunit 3)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Scn3b (sodium voltage-gated channel beta subunit 3)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Scn3b (sodium voltage-gated channel beta subunit 3)
Pan paniscus (bonobo/pygmy chimpanzee) : SCN3B (sodium voltage-gated channel beta subunit 3)
Canis lupus familiaris (dog) : SCN3B (sodium voltage-gated channel beta subunit 3)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Scn3b (sodium voltage-gated channel beta subunit 3)
Sus scrofa (pig) : SCN3B (sodium voltage-gated channel beta subunit 3)
Chlorocebus sabaeus (African green monkey) : SCN3B (sodium voltage-gated channel beta subunit 3)
Heterocephalus glaber (naked mole-rat) : Scn3b (sodium voltage-gated channel beta subunit 3)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38 Ensembl940,269,217 - 40,291,618 (+)EnsemblGRCm38mm10GRCm38
GRCm38940,269,216 - 40,291,618 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37940,076,801 - 40,099,203 (+)NCBIGRCm37mm9NCBIm37
MGSCv36940,019,969 - 40,041,678 (+)NCBImm8
Celera937,506,998 - 37,529,283 (+)NCBICelera
Cytogenetic Map9A5.1NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Scn3b
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1332251
Created: 2005-02-01
Species: Mus musculus
Last Modified: 2020-03-25
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.