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Gene: Map1lc3a (microtubule-associated protein 1 light chain 3 alpha) Mus musculus
Symbol: Map1lc3a
Name: microtubule-associated protein 1 light chain 3 alpha
Description: Predicted to have microtubule binding activity; phosphatidylethanolamine binding activity; and ubiquitin protein ligase binding activity. Predicted to be involved in autophagy of mitochondrion; cellular response to nitrogen starvation; and macroautophagy. Localizes to the autophagosome membrane. Human ortholog(s) of this gene implicated in glioblastoma multiforme. Is expressed in several structures, including central nervous system; heart; limb; nasal cavity; and peripheral nervous system ganglion. Orthologous to human MAP1LC3A (microtubule associated protein 1 light chain 3 alpha); PARTICIPATES IN autophagy pathway; INTERACTS WITH 17alpha-ethynylestradiol; 2,3',4,4',5-Pentachlorobiphenyl; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 1010001H21Rik; 4922501H04Rik; autophagy-related protein LC3 A; autophagy-related ubiquitin-like modifier LC3 A; LC3; LC3a; MAP1 light chain 3-like protein 1; MAP1A/MAP1B LC3 A; MAP1A/MAP1B light chain 3 A; microtubule-associated proteins 1A/1B light chain 3A
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38 Ensembl2155,276,297 - 155,278,073 (+)Ensembl
GRCm382155,276,364 - 155,278,073 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv372155,102,180 - 155,103,809 (+)NCBIGRCm37mm9NCBIm37
MGSCv362154,967,905 - 154,969,511 (+)NCBImm8
Celera2161,208,920 - 161,210,629 (+)NCBICelera
Cytogenetic Map2 H1NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Map1lc3a
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1332294
Created: 2005-02-01
Species: Mus musculus
Last Modified: 2019-12-10
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.