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Gene: Inpp5e (inositol polyphosphate-5-phosphatase E) Mus musculus
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Symbol: Inpp5e
Name: inositol polyphosphate-5-phosphatase E
Description: Exhibits phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity. Involved in inositol phosphate dephosphorylation; negative regulation of protein localization to cilium; and phosphatidylinositol dephosphorylation. Localizes to Golgi membrane and axoneme. Is expressed in several structures, including alimentary system; eye; genitourinary system; nervous system; and respiratory system. Human ortholog(s) of this gene implicated in Joubert syndrome and Joubert syndrome 1. Orthologous to human INPP5E (inositol polyphosphate-5-phosphatase E); PARTICIPATES IN phosphoinositide metabolic pathway; inositol phosphate metabolic pathway; phosphatidylinositol 3-kinase signaling pathway; INTERACTS WITH 1,2-dichloroethane; 2,3,7,8-tetrachlorodibenzodioxine; aflatoxin B1.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 1200002L24Rik; 72 kDa inositol polyphosphate 5-phosphatase; 72kDa; inositol polyphosphate-5-phosphatase, 72 kDa; mKIAA0123; phosphatidylinositol 4,5-bisphosphate 5-phosphatase; phosphatidylinositol polyphosphate 5-phosphatase type IV; phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase; phosphatidylinositol-4,5-bisphosphate 5-phosphatase
Orthologs:
Homo sapiens (human) : INPP5E (inositol polyphosphate-5-phosphatase E)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Inpp5e (inositol polyphosphate-5-phosphatase E)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Inpp5e (inositol polyphosphate-5-phosphatase E)
Pan paniscus (bonobo/pygmy chimpanzee) : INPP5E (inositol polyphosphate-5-phosphatase E)
Canis lupus familiaris (dog) : INPP5E (inositol polyphosphate-5-phosphatase E)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Inpp5e (inositol polyphosphate-5-phosphatase E)
Sus scrofa (pig) : INPP5E (inositol polyphosphate-5-phosphatase E)
Chlorocebus sabaeus (African green monkey) : INPP5E (inositol polyphosphate-5-phosphatase E)
Heterocephalus glaber (naked mole-rat) : Inpp5e (inositol polyphosphate-5-phosphatase E)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38 Ensembl226,396,249 - 26,409,203 (-)EnsemblGRCm38mm10GRCm38
GRCm38226,396,249 - 26,409,244 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37226,251,769 - 26,264,708 (-)NCBIGRCm37mm9NCBIm37
MGSCv36226,218,258 - 26,231,197 (-)NCBImm8
Celera226,113,925 - 26,126,902 (-)NCBICelera
Cytogenetic Map2A3NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
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References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Inpp5e
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1332343
Created: 2005-02-01
Species: Mus musculus
Last Modified: 2020-06-30
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.