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Gene: Unc119 (unc-119 lipid binding chaperone) Mus musculus
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Symbol: Unc119
Name: unc-119 lipid binding chaperone
Description: Predicted to have lipid binding activity. Involved in lipoprotein transport; negative regulation of caveolin-mediated endocytosis; and negative regulation of clathrin-dependent endocytosis. Predicted to localize to the intercellular bridge and microtubule cytoskeleton. Human ortholog(s) of this gene implicated in idiopathic CD4-positive T-lymphocytopenia. Is expressed in foregut; liver lobe; male reproductive gland or organ; metanephros; and retina layer. Orthologous to human UNC119 (unc-119 lipid binding chaperone).
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: D11Bhm52; HRG4; MRG4; protein unc-119 homolog A; retinal gene 4; retinal protein 4; Rg4; Rtg4; Unc119h
Orthologs:
Homo sapiens (human) : UNC119 (unc-119 lipid binding chaperone)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Unc119 (unc-119 lipid binding chaperone)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Unc119 (unc-119 lipid binding chaperone)
Pan paniscus (bonobo/pygmy chimpanzee) : UNC119 (unc-119 lipid binding chaperone)
Canis lupus familiaris (dog) : UNC119 (unc-119 lipid binding chaperone)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Unc119 (unc-119 lipid binding chaperone)
Sus scrofa (pig) : UNC119 (unc-119 lipid binding chaperone)
Chlorocebus sabaeus (green monkey) : UNC119 (unc-119 lipid binding chaperone)
Heterocephalus glaber (naked mole-rat) : Unc119 (unc-119 lipid binding chaperone)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38 Ensembl1178,343,482 - 78,349,164 (+)Ensembl
GRCm381178,343,495 - 78,349,164 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371178,157,024 - 78,162,658 (+)NCBIGRCm37mm9NCBIm37
MGSCv361178,159,717 - 78,165,351 (+)NCBImm8
Celera1187,975,604 - 87,981,238 (+)NCBICelera
Cytogenetic Map11 B5NCBI
cM Map1146.74NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
Nomenclature History
 
More on Unc119
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1332505
Created: 2005-02-01
Species: Mus musculus
Last Modified: 2020-01-21
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.