Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: KLHL13 (kelch like family member 13) Homo sapiens
Symbol: KLHL13
Name: kelch like family member 13
Description: This gene encodes a BTB and kelch domain containing protein and belongs to the kelch repeat domain containing superfamily of proteins. The encoded protein functions as an adaptor protein that complexes with Cullin 3 and other proteins to form the Cullin 3-based E3 ubiquitin-protein ligase complex. This complex is necessary for proper chromosome segregation and completion of cytokinesis. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Mar 2010]
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: BKLHD2; BTB and kelch domain containing 2; FLJ10262; kelch-like 13; kelch-like family member 13; kelch-like protein 13; KIAA1309; MGC74791
Mus musculus (house mouse) : Klhl13 (kelch-like 13)  MGI  Alliance
Rattus norvegicus (Norway rat) : Klhl13 (kelch-like family member 13)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Klhl13 (kelch like family member 13)
Pan paniscus (bonobo/pygmy chimpanzee) : KLHL13 (kelch like family member 13)
Canis lupus familiaris (dog) : KLHL13 (kelch like family member 13)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Klhl13 (kelch like family member 13)
Sus scrofa (pig) : KLHL13 (kelch like family member 13)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38X117,897,813 - 118,117,340 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37X117,031,776 - 117,251,303 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36X116,915,804 - 116,990,881 (-)NCBINCBI36hg18NCBI36
Build 34X116,813,657 - 116,888,735NCBI
CeleraX117,486,583 - 117,706,100 (-)NCBI
Cytogenetic MapXq24NCBI
HuRefX106,526,310 - 106,745,823 (-)NCBIHuRef
CHM1_1X116,942,701 - 117,162,205 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on KLHL13
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1342476
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2019-07-09
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.