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Gene: KLHL13 (kelch like family member 13) Homo sapiens
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Symbol: KLHL13
Name: kelch like family member 13
Description: This gene encodes a BTB and kelch domain containing protein and belongs to the kelch repeat domain containing superfamily of proteins. The encoded protein functions as an adaptor protein that complexes with Cullin 3 and other proteins to form the Cullin 3-based E3 ubiquitin-protein ligase complex. This complex is necessary for proper chromosome segregation and completion of cytokinesis. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Mar 2010]
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: BKLHD2; BTB and kelch domain containing 2; FLJ10262; kelch-like 13; kelch-like family member 13; kelch-like protein 13; KIAA1309; MGC74791
Orthologs:
Mus musculus (house mouse) : Klhl13 (kelch-like 13)  MGI  Alliance
Rattus norvegicus (Norway rat) : Klhl13 (kelch-like family member 13)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Klhl13 (kelch like family member 13)
Pan paniscus (bonobo/pygmy chimpanzee) : KLHL13 (kelch like family member 13)
Canis lupus familiaris (dog) : KLHL13 (kelch like family member 13)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Klhl13 (kelch like family member 13)
Sus scrofa (pig) : KLHL13 (kelch like family member 13)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38X117,897,813 - 118,117,340 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37X117,031,776 - 117,251,303 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36X116,915,804 - 116,990,881 (-)NCBINCBI36hg18NCBI36
Build 34X116,813,657 - 116,888,735NCBI
CeleraX117,486,583 - 117,706,100 (-)NCBI
Cytogenetic MapXq24NCBI
HuRefX106,526,310 - 106,745,823 (-)NCBIHuRef
CHM1_1X116,942,701 - 117,162,205 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on KLHL13
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1342476
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2019-07-09
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.