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Gene: CHMP4A (charged multivesicular body protein 4A) Homo sapiens
Symbol: CHMP4A
Name: charged multivesicular body protein 4A
Description: Exhibits ATPase binding activity and protein homodimerization activity. Involved in several processes, including midbody abscission; negative regulation of autophagosome assembly; and plasma membrane tubulation. Localizes to several cellular components, including the ESCRT III complex; cytoplasmic side of plasma membrane; and midbody. Colocalizes with the endosome and plasma membrane.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: C14orf123; CHMP4; CHMP4B; chromatin modifying protein 4A; chromatin-modifying protein 4a; chromosome 14 open reading frame 123; FLJ61658; hSnf-1; HSPC134; hVps32-1; MGC142093; MGC142095; Shax2; SNF7; SNF7 homolog associated with Alix-2; Snf7 homologue associated with Alix 2; SNF7-1; vacuolar protein sorting-associated protein 32-1; VPS32-1; VPS32A
Pan paniscus (bonobo/pygmy chimpanzee) : CHMP4A (charged multivesicular body protein 4A)
Canis lupus familiaris (dog) : CHMP4A (charged multivesicular body protein 4A)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Chmp4a (charged multivesicular body protein 4A)
Sus scrofa (pig) : CHMP4A (charged multivesicular body protein 4A)
more info ...
Related Pseudogenes: CHMP4AP1  
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38 Ensembl1424,209,583 - 24,213,869 (-)Ensembl
GRCh381424,209,615 - 24,213,488 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh371424,678,787 - 24,683,036 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361423,748,627 - 23,753,025 (-)NCBINCBI36hg18NCBI36
Build 341423,748,626 - 23,753,025NCBI
Celera144,543,256 - 4,547,822 (-)NCBI
Cytogenetic Map14q12NCBI
HuRef144,793,794 - 4,798,040 (-)NCBIHuRef
CHM1_11424,677,437 - 24,681,686 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on CHMP4A
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1342527
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2019-12-25
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.