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Gene: TF (transferrin) Homo sapiens
Symbol: TF
Name: transferrin
CRRD ID: 1342593
Description: Exhibits ferrous iron binding activity; iron chaperone activity; and transferrin receptor binding activity. Involved in cellular response to iron ion; positive regulation of receptor-mediated endocytosis; and regulation of iron ion transport. Localizes to several cellular components, including HFE-transferrin receptor complex; basal plasma membrane; and cytoplasmic vesicle. Implicated in anemia; atransferrinemia; glucose metabolism disease (multiple); iron deficiency anemia; and restless legs syndrome. Biomarker of glomerulonephritis; hypertension; and membranous glomerulonephritis.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: beta-1 metal-binding globulin; DKFZp781D0156; epididymis secretory sperm binding protein Li 71p; HEL-S-71p; PRO1557; PRO2086; serotransferrin; siderophilin; TFQTL1
Mus musculus (house mouse) : Trf (transferrin)  MGI  Alliance
Rattus norvegicus (Norway rat) : Tf (transferrin)  Alliance
Pan paniscus (bonobo/pygmy chimpanzee) : LOC100995326 (serotransferrin)
Canis lupus familiaris (dog) : LOC477072 (serotransferrin)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Tf (transferrin)
Sus scrofa (pig) : TF (transferrin)
Chlorocebus sabaeus (African green monkey) : TF (transferrin)
more info ...
Related Pseudogenes: INHCAP  
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38.p13 Ensembl3133,746,040 - 133,796,641 (+)EnsemblGRCh38hg38GRCh38
GRCh383133,661,998 - 133,796,641 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh373133,464,977 - 133,497,850 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 363134,947,925 - 134,980,325 (+)NCBINCBI36hg18NCBI36
Build 343134,947,932 - 134,980,333NCBI
Celera3131,892,092 - 131,924,970 (+)NCBI
Cytogenetic Map3q22.1NCBI
HuRef3130,844,635 - 130,877,514 (+)NCBIHuRef
CHM1_13133,428,386 - 133,461,264 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
More on TF
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1342593
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2020-11-10
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.