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Gene: ELAC2 (elaC ribonuclease Z 2) Homo sapiens
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Symbol: ELAC2
Name: elaC ribonuclease Z 2
Description: Exhibits tRNA-specific ribonuclease activity. Involved in mitochondrial tRNA 3'-trailer cleavage, endonucleolytic. Localizes to mitochondrion and nucleoplasm. Implicated in combined oxidative phosphorylation deficiency 17.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: COXPD17; elaC homolog 2; elaC homolog protein 2; elaC-like protein 2; ELC2; FLJ10530; FLJ36693; FLJ42848; heredity prostate cancer protein 2; HPC2; putative prostate cancer susceptibility protein HPC2/ELAC2; ribonuclease Z 2; RNase Z 2; tRNA 3 endonuclease 2; tRNase Z (long form); tRNase Z 2; zinc phosphodiesterase ELAC protein 2
Orthologs:
Mus musculus (house mouse) : Elac2 (elaC ribonuclease Z 2)  MGI  Alliance
Rattus norvegicus (Norway rat) : Elac2 (elaC ribonuclease Z 2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Elac2 (elaC ribonuclease Z 2)
Pan paniscus (bonobo/pygmy chimpanzee) : ELAC2 (elaC ribonuclease Z 2)
Canis lupus familiaris (dog) : ELAC2 (elaC ribonuclease Z 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Elac2 (elaC ribonuclease Z 2)
Sus scrofa (pig) : ELAC2 (elaC ribonuclease Z 2)
Chlorocebus sabaeus (African green monkey) : ELAC2 (elaC ribonuclease Z 2)
Heterocephalus glaber (naked mole-rat) : Elac2 (elaC ribonuclease Z 2)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38 Ensembl1712,991,612 - 13,018,065 (-)EnsemblGRCh38hg38GRCh38
GRCh381712,991,612 - 13,018,064 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh371712,894,929 - 12,921,381 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361712,836,427 - 12,862,084 (-)NCBINCBI36hg18NCBI36
Build 341712,836,434 - 12,862,049NCBI
Celera1712,920,244 - 12,946,689 (-)NCBI
Cytogenetic Map17p12NCBI
HuRef1712,790,637 - 12,816,700 (-)NCBIHuRef
CHM1_11712,903,688 - 12,930,141 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Candidate Gene Status
Comparative Map Data
Position Markers
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on ELAC2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1342597
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2020-06-18
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.