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Gene: SRSF6 (serine and arginine rich splicing factor 6) Homo sapiens
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Symbol: SRSF6
Name: serine and arginine rich splicing factor 6
Description: Exhibits pre-mRNA binding activity. Involved in several processes, including mRNA splicing, via spliceosome; regulation of epithelial cell proliferation; and regulation of mRNA splicing, via spliceosome. Localizes to nuclear speck. Implicated in proliferative diabetic retinopathy and spermatogenic failure 3. Biomarker of Huntington's disease; clear cell renal cell carcinoma; colon adenocarcinoma; lung cancer; and skin cancer.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: arginine/serine-rich splicing factor 6; B52; epididymis secretory protein Li 91; FLJ08061; HEL-S-91; MGC5045; pre-mRNA splicing factor SRP55; pre-mRNA-splicing factor SRP55; serine/arginine-rich splicing factor 6; SFRS6; splicing factor, arginine/serine-rich 6; splicing factor, arginine/serine-rich, 55 kDa; SR splicing factor 6; SRP55
Orthologs:
Mus musculus (house mouse) : Srsf6 (serine and arginine-rich splicing factor 6)  MGI  Alliance
Rattus norvegicus (Norway rat) : Srsf6 (serine and arginine rich splicing factor 6)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Srsf6 (serine and arginine rich splicing factor 6)
Pan paniscus (bonobo/pygmy chimpanzee) : SRSF6 (serine and arginine rich splicing factor 6)
Canis lupus familiaris (dog) : SRSF6 (serine and arginine rich splicing factor 6)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Srsf6 (serine and arginine rich splicing factor 6)
Sus scrofa (pig) : SRSF6 (serine and arginine rich splicing factor 6)
Chlorocebus sabaeus (African green monkey) : SRSF6 (serine and arginine rich splicing factor 6)
Heterocephalus glaber (naked mole-rat) : Srsf6 (serine and arginine rich splicing factor 6)
more info ...
Related Pseudogenes: SRSF6P1   SRSF6P2  
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl2043,457,893 - 43,466,046 (+)EnsemblGRCh38hg38GRCh38
GRCh382043,457,893 - 43,464,243 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh372042,086,504 - 42,092,245 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362041,519,932 - 41,525,655 (+)NCBINCBI36hg18NCBI36
Build 342041,519,931 - 41,525,655NCBI
Celera2038,793,993 - 38,799,734 (+)NCBI
Cytogenetic Map20q13.11NCBI
HuRef2038,822,762 - 38,828,474 (+)NCBIHuRef
CHM1_12041,990,350 - 41,996,091 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
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References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
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Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on SRSF6
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1342668
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2020-08-04
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.