Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: DCT (dopachrome tautomerase) Homo sapiens
Analyze
Symbol: DCT
Name: dopachrome tautomerase
Description: Predicted to have dopachrome isomerase activity. Predicted to be involved in developmental pigmentation; generation of neurons; and melanin biosynthetic process from tyrosine. Localizes to the intracellular membrane-bounded organelle and plasma membrane; PARTICIPATES IN alkaptonuria pathway; disulfiram pharmacodynamics pathway; dopamine beta-hydroxylase deficiency pathway; INTERACTS WITH (+)-artemisinic acid; 2,3,7,8-tetrachlorodibenzodioxine; 5-fluorouracil.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: dopachrome delta-isomerase; dopachrome tautomerase (dopachrome delta-isomerase, tyrosine-related protein 2); DT; L-dopachrome Delta-isomerase; L-dopachrome isomerase; L-dopachrome tautomerase; TRP-2; TRP2; tyrosinase related protein-2; tyrosinase-related protein 2; tyrosine-related protein 2; TYRP2
Orthologs:
Mus musculus (house mouse) : Dct (dopachrome tautomerase)  MGI  Alliance
Rattus norvegicus (Norway rat) : Dct (dopachrome tautomerase)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Dct (dopachrome tautomerase)
Pan paniscus (bonobo/pygmy chimpanzee) : DCT (dopachrome tautomerase)
Canis lupus familiaris (dog) : DCT (dopachrome tautomerase)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Dct (dopachrome tautomerase)
Sus scrofa (pig) : DCT (dopachrome tautomerase)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381394,436,811 - 94,549,406 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh371395,091,835 - 95,131,936 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361393,889,836 - 93,929,924 (-)NCBINCBI36hg18NCBI36
Build 341393,889,839 - 93,929,924NCBI
Celera1375,940,079 - 75,980,144 (-)NCBI
Cytogenetic Map13q32.1NCBI
HuRef1375,688,784 - 75,728,851 (-)NCBIHuRef
CHM1_11395,059,070 - 95,171,100 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on DCT
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1342702
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2019-11-26
Status: ACTIVE



NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.