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Gene: H4C2 (H4 clustered histone 2) Homo sapiens
Symbol: H4C2
Name: H4 clustered histone 2
Description: Exhibits protein domain specific binding activity. Involved in DNA replication-dependent nucleosome assembly; DNA replication-independent nucleosome assembly; and negative regulation of megakaryocyte differentiation. Localizes to nuclear nucleosome.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: H4 histone family, member I; H4-16; H4/I; H4C1; H4C11; H4C12; H4C13; H4C14; H4C15; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4FI; HIST1H4A; HIST1H4B; HIST1H4C; HIST1H4D; HIST1H4E; HIST1H4F; HIST1H4H; HIST1H4I; HIST1H4J; HIST1H4K; HIST1H4L; HIST2H4A; HIST2H4B; HIST4H4; histone 1, H4b; histone cluster 1 H4 family member b; histone cluster 1, H4b; histone H4
Mus musculus (house mouse) : H4f16 (H4 histone 16)  MGI  Alliance
Rattus norvegicus (Norway rat) : Hist2h4 (histone cluster 2, H4)  Alliance
Pan paniscus (bonobo/pygmy chimpanzee) : LOC100992212 (histone H4)
Canis lupus familiaris (dog) : H4C14 (H4 clustered histone 14)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : LOC106145261 (histone H4)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38.p13 Ensembl626,026,815 - 26,027,252 (-)EnsemblGRCh38hg38GRCh38
GRCh38626,026,896 - 26,027,283 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37626,027,124 - 26,027,480 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36626,135,103 - 26,135,459 (-)NCBINCBI36hg18NCBI36
Build 34626,135,102 - 26,135,459NCBI
Celera627,254,348 - 27,254,704 (-)NCBI
Cytogenetic Map6p22.2NCBI
HuRef625,970,187 - 25,970,543 (-)NCBIHuRef
CHM1_1626,029,397 - 26,029,753 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers



Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on H4C2
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1342856
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2020-07-28
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.