Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: NCL (nucleolin) Homo sapiens
Analyze
Symbol: NCL
Name: nucleolin
Description: Exhibits several functions, including DNA topoisomerase binding activity; nucleic acid binding activity; and protein C-terminus binding activity. Involved in angiogenesis; negative regulation of translation; and positive regulation of transcription of nucleolar large rRNA by RNA polymerase I. Localizes to several cellular components, including the cell cortex; cytoplasmic ribonucleoprotein granule; and nuclear lumen.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: C23; FLJ45706; FLJ59041; Nsr1
Orthologs:
Mus musculus (house mouse) : Ncl (nucleolin)  MGI  Alliance
Rattus norvegicus (Norway rat) : Ncl (nucleolin)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Ncl (nucleolin)
Pan paniscus (bonobo/pygmy chimpanzee) : NCL (nucleolin)
Canis lupus familiaris (dog) : NCL (nucleolin)
Sus scrofa (pig) : NCL (nucleolin)
more info ...
Related Pseudogenes: NCLP1   NCLP2  
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38 Ensembl2231,453,531 - 231,483,641 (-)Ensembl
GRCh382231,453,531 - 231,464,484 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh372232,319,459 - 232,329,208 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362232,027,703 - 232,037,449 (-)NCBINCBI36hg18NCBI36
Build 342232,144,964 - 232,154,710NCBI
Celera2226,095,812 - 226,105,543 (-)NCBI
Cytogenetic Map2q37.1NCBI
HuRef2224,160,942 - 224,170,673 (-)NCBIHuRef
CHM1_12232,325,275 - 232,335,021 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
 
More on NCL
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1342988
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2020-01-07
Status: ACTIVE



NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.