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Gene: RAPGEF5 (Rap guanine nucleotide exchange factor 5) Homo sapiens
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Symbol: RAPGEF5
Name: Rap guanine nucleotide exchange factor 5
Description: Exhibits GTP-dependent protein binding activity and Rap guanyl-nucleotide exchange factor activity. Predicted to be involved in small GTPase mediated signal transduction. Localizes to the nuclear body.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: GFR; guanine nucleotide exchange factor for Rap1; KIAA0277; M-Ras-regulated GEF; M-Ras-regulated Rap GEF; MR-GEF; Rap guanine nucleotide exchange factor (GEF) 5; related to Epac; REPAC
Orthologs:
Mus musculus (house mouse) : Rapgef5 (Rap guanine nucleotide exchange factor (GEF) 5)  MGI  Alliance
Rattus norvegicus (Norway rat) : Rapgef5 (Rap guanine nucleotide exchange factor 5)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Rapgef5 (Rap guanine nucleotide exchange factor 5)
Pan paniscus (bonobo/pygmy chimpanzee) : RAPGEF5 (Rap guanine nucleotide exchange factor 5)
Canis lupus familiaris (dog) : RAPGEF5 (Rap guanine nucleotide exchange factor 5)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Rapgef5 (Rap guanine nucleotide exchange factor 5)
Sus scrofa (pig) : RAPGEF5 (Rap guanine nucleotide exchange factor 5)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38722,118,236 - 22,357,154 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37722,157,908 - 22,396,751 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36722,124,433 - 22,363,058 (-)NCBINCBI36hg18NCBI36
Celera722,143,557 - 22,382,091 (-)NCBI
Cytogenetic Map7p15.3NCBI
HuRef722,043,471 - 22,243,092 (-)NCBIHuRef
CHM1_1722,158,708 - 22,397,156 (-)NCBICHM1_1
CRA_TCAGchr7v2722,209,210 - 22,447,742 (-)NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on RAPGEF5
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1343059
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2019-10-16
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.