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Gene: CA5B (carbonic anhydrase 5B) Homo sapiens
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Symbol: CA5B
Name: carbonic anhydrase 5B
Description: Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. They participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, and gastric acid. They show extensive diversity in tissue distribution and in their subcellular localization. This gene encodes carbonic anhydrase 5B. CA5B, and the related CA5A gene, has its expression localized in the mitochondria though CA5B has a wider tissue distribution than CA5A, which is restricted to the liver, kidneys, and skeletal muscle. A carbonic anhydrase pseudogene (CA5BP1) is adjacent to the CA5B gene and these two loci produce CA5BP1-CA5B readthrough transcripts. [provided by RefSeq, Jan 2019]
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: CA-VB; carbonate dehydratase VB; carbonic anhydrase 5B, mitochondrial; carbonic anhydrase VB, mitochondrial; carbonic dehydratase; CAVB; MGC39962
Orthologs:
Mus musculus (house mouse) : Car5b (carbonic anhydrase 5b, mitochondrial)  MGI  Alliance
Rattus norvegicus (Norway rat) : Ca5b (carbonic anhydrase 5B)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Ca5b (carbonic anhydrase 5B)
Pan paniscus (bonobo/pygmy chimpanzee) : CA5B (carbonic anhydrase 5B)
Canis lupus familiaris (dog) : CA5B (carbonic anhydrase 5B)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Ca5b (carbonic anhydrase 5B)
Sus scrofa (pig) : CA5B (carbonic anhydrase 5B)
more info ...
Related Pseudogenes: CA5BP1  
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38X15,738,281 - 15,787,625 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37X15,756,412 - 15,805,748 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36X15,666,333 - 15,715,669 (+)NCBINCBI36hg18NCBI36
Build 34X15,516,081 - 15,562,315NCBI
CeleraX19,872,853 - 19,923,232 (+)NCBI
Cytogenetic MapXp22.2NCBI
HuRefX13,510,606 - 13,559,489 (+)NCBIHuRef
CHM1_1X15,787,366 - 15,836,721 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


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References - uncurated

Genomics

Comparative Map Data
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Sequence

Nucleotide Sequences
Protein Sequences
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Additional Information

External Database Links
Nomenclature History
 
More on CA5B
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1343079
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2019-07-09
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.