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Gene: NONO (non-POU domain containing octamer binding) Homo sapiens
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Symbol: NONO
Name: non-POU domain containing octamer binding
Description: This gene encodes an RNA-binding protein which plays various roles in the nucleus, including transcriptional regulation and RNA splicing. A rearrangement between this gene and the transcription factor E3 gene has been observed in papillary renal cell carcinoma. Alternatively spliced transcript variants have been described. Pseudogenes exist on Chromosomes 2 and 16. [provided by RefSeq, Feb 2009]
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: 54 kDa nuclear RNA- and DNA-binding protein; 55 kDa nuclear protein; DNA-binding p52/p100 complex, 52 kDa subunit; MRXS34; NMT55; non-POU domain containing octamer-binding; non-POU domain containing, octamer-binding; non-POU domain-containing octamer (ATGCAAAT) binding protein; non-POU domain-containing octamer-binding protein; NRB54; P54; p54(nrb); P54NRB; PPP1R114
Orthologs:
Mus musculus (house mouse) : Nono (non-POU-domain-containing, octamer binding protein)  MGI  Alliance
Rattus norvegicus (Norway rat) : Nono (non-POU domain containing, octamer-binding)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Nono (non-POU domain containing octamer binding)
Pan paniscus (bonobo/pygmy chimpanzee) : NONO (non-POU domain containing octamer binding)
Canis lupus familiaris (dog) : NONO (non-POU domain containing octamer binding)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Nono (non-POU domain containing octamer binding)
more info ...
Related Pseudogenes: NONOP1   NONOP2  
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38X71,283,192 - 71,301,168 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37X70,503,042 - 70,521,018 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36X70,420,192 - 70,437,743 (+)NCBINCBI36hg18NCBI36
Build 34X70,286,487 - 70,304,037NCBI
CeleraX70,856,920 - 70,874,896 (+)NCBI
Cytogenetic MapXq13.1NCBI
HuRefX64,319,299 - 64,337,309 (+)NCBIHuRef
CHM1_1X70,396,097 - 70,414,071 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on NONO
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1343083
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2019-08-06
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.