Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: HRC (histidine rich calcium binding protein) Homo sapiens
Symbol: HRC
Name: histidine rich calcium binding protein
Description: Exhibits ATPase binding activity; calcium ion binding activity; and ion channel binding activity. Involved in several processes, including positive regulation of relaxation of cardiac muscle; regulation of heart contraction; and regulation of release of sequestered calcium ion into cytosol. Localizes to Z disc.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: MGC133236; sarcoplasmic reticulum histidine-rich calcium-binding protein
Mus musculus (house mouse) : Hrc (histidine rich calcium binding protein)  MGI  Alliance
Rattus norvegicus (Norway rat) : Hrc (histidine rich calcium binding protein)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Hrc (histidine rich calcium binding protein)
Pan paniscus (bonobo/pygmy chimpanzee) : HRC (histidine rich calcium binding protein)
Canis lupus familiaris (dog) : HRC (histidine rich calcium binding protein)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Hrc (histidine rich calcium binding protein)
Sus scrofa (pig) : HRC (histidine rich calcium binding protein)
Chlorocebus sabaeus (African green monkey) : HRC (histidine rich calcium binding protein)
Heterocephalus glaber (naked mole-rat) : Hrc (histidine rich calcium binding protein)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38.p13 Ensembl1949,151,198 - 49,155,396 (-)EnsemblGRCh38hg38GRCh38
GRCh381949,151,198 - 49,155,464 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh371949,654,455 - 49,658,686 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361954,346,267 - 54,350,493 (-)NCBINCBI36hg18NCBI36
Build 341954,346,269 - 54,350,476NCBI
Celera1946,521,679 - 46,525,908 (-)NCBI
Cytogenetic Map19q13.33NCBI
HuRef1946,030,689 - 46,034,918 (-)NCBIHuRef
CHM1_11949,656,583 - 49,660,812 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
More on HRC
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1343095
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2020-08-04
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.