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Gene: CAV2 (caveolin 2) Homo sapiens
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Symbol: CAV2
Name: caveolin 2
Description: Exhibits D1 dopamine receptor binding activity and protein homodimerization activity. Involved in several processes, including caveola assembly; positive regulation by host of viral release from host cell; and positive regulation of signal transduction. Localizes to several cellular components, including the caveola; extrinsic component of cytoplasmic side of plasma membrane; and perinuclear region of cytoplasm. Colocalizes with the focal adhesion. Implicated in low tension glaucoma and primary open angle glaucoma. Biomarker of tongue squamous cell carcinoma.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: CAV; caveolae protein, 20-kD; caveolin 2 isoform a and b; caveolin-2; MGC12294
Orthologs:
Mus musculus (house mouse) : Cav2 (caveolin 2)  MGI  Alliance
Rattus norvegicus (Norway rat) : Cav2 (caveolin 2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Cav2 (caveolin 2)
Pan paniscus (bonobo/pygmy chimpanzee) : CAV2 (caveolin 2)
Canis lupus familiaris (dog) : CAV2 (caveolin 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Cav2 (caveolin 2)
Sus scrofa (pig) : CAV2 (caveolin 2)
Chlorocebus sabaeus (African green monkey) : CAV2 (caveolin 2)
Heterocephalus glaber (naked mole-rat) : Cav2 (caveolin 2)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38 Ensembl7116,287,380 - 116,508,541 (+)Ensembl
GRCh387116,499,738 - 116,508,541 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh377116,139,655 - 116,148,595 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 367115,926,680 - 115,935,831 (+)NCBINCBI36hg18NCBI36
Build 347115,733,394 - 115,742,545NCBI
Celera7110,946,853 - 110,956,001 (+)NCBI
Cytogenetic Map7q31.2NCBI
HuRef7110,505,654 - 110,514,581 (+)NCBIHuRef
CHM1_17116,073,006 - 116,081,933 (+)NCBICHM1_1
CRA_TCAGchr7v27115,535,087 - 115,544,028 (+)NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Candidate Gene Status
Comparative Map Data
Position Markers
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
 
More on CAV2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1343117
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2019-12-25
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.