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Gene: TBX22 (T-box transcription factor 22) Homo sapiens
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Symbol: TBX22
Name: T-box transcription factor 22
Description: This gene is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. Mutations in this gene have been associated with the inherited X-linked disorder, Cleft palate with ankyloglossia, and it is believed to play a major role in human palatogenesis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: ABERS; cleft palate and/or ankyloglossia; CLPA; CPX; dJ795G23.1; T-box 22; T-box protein 22; T-box transcription factor TBX22; TBXX
Orthologs:
Mus musculus (house mouse) : Tbx22 (T-box 22)  MGI  Alliance
Rattus norvegicus (Norway rat) : Tbx22 (T-box transcription factor 22)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Tbx22 (T-box transcription factor 22)
Pan paniscus (bonobo/pygmy chimpanzee) : TBX22 (T-box transcription factor 22)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Tbx22 (T-box transcription factor 22)
Sus scrofa (pig) : TBX22 (T-box transcription factor 22)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38X80,014,753 - 80,031,774 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37X79,270,255 - 79,287,268 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36X79,156,911 - 79,173,924 (+)NCBINCBI36hg18NCBI36
Build 34X79,083,886 - 79,093,413NCBI
CeleraX79,510,188 - 79,527,202 (+)NCBI
Cytogenetic MapXq21.1NCBI
HuRefX72,851,434 - 72,868,446 (+)NCBIHuRef
CHM1_1X79,163,473 - 79,180,486 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on TBX22
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1343120
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2019-09-12
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.