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Gene: GEMIN8 (gem nuclear organelle associated protein 8) Homo sapiens
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Symbol: GEMIN8
Name: gem nuclear organelle associated protein 8
Description: The protein encoded by this gene is part of the SMN complex, which is necessary for spliceosomal snRNP assembly in the cytoplasm and pre-mRNA splicing in the nucleus. The encoded protein binds to both SMN1 and the GEMIN6/GEMIN7 heterodimer, mediating their interaction. This protein is found in nuclear Gemini of Cajal bodies (gems) and in the cytoplasm. Three transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, May 2010]
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: FAM51A1; family with sequence similarity 51, member A1; FLJ20514; FLJ43072; gem (nuclear organelle) associated protein 8; gem-associated protein 8; gemin-8
Orthologs:
Mus musculus (house mouse) : Gemin8 (gem nuclear organelle associated protein 8)  MGI  Alliance
Rattus norvegicus (Norway rat) : Gemin8 (gem (nuclear organelle) associated protein 8)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Gemin8 (gem nuclear organelle associated protein 8)
Pan paniscus (bonobo/pygmy chimpanzee) : GEMIN8 (gem nuclear organelle associated protein 8)
Canis lupus familiaris (dog) : GEMIN8 (gem nuclear organelle associated protein 8)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Gemin8 (gem nuclear organelle associated protein 8)
Sus scrofa (pig) : GEMIN8 (gem nuclear organelle associated protein 8)
more info ...
Related Pseudogenes: GEMIN8P1   GEMIN8P2   GEMIN8P3   GEMIN8P4  
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38X14,002,494 - 14,029,918 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37X14,024,845 - 14,048,035 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36X13,934,766 - 13,957,956 (-)NCBINCBI36hg18NCBI36
Build 34X13,786,054 - 13,807,668NCBI
CeleraX18,140,750 - 18,163,940 (-)NCBI
Cytogenetic MapXp22.2NCBI
HuRefX11,782,027 - 11,801,284 (-)NCBIHuRef
CHM1_1X14,055,283 - 14,078,493 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on GEMIN8
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1343150
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2019-09-12
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.